Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia
Background and Objective: Preeclampsia is one of the most critical complications of pregnancy observed in 2%-8% of all pregnancies. Severe preeclampsia has many maternal and neonatal complications that are more prevalent in early-onset preeclampsia. The present study aimed to determine the prevalenc...
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Hamadan University of Medical Sciences
2021-06-01
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doaj-45a4c63589194aeb92cf1380cfce1de02021-06-29T08:11:58ZfasHamadan University of Medical Sciencesپزشکی بالینی ابن سینا2588-722X2588-72382021-06-012812835Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe PreeclampsiaZohreh Tabasi0Elahe Mesdaghinia1Masoumeh Abedzadeh-Kalahroudi2Hossein Akbari3Mahsa Bandagi-Motlagh4 Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran Associate Professor, Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, Iran Associate Professor, Department of Statistics and Epidemiology, Faculty of Health, Kashan University of Medical Sciences, Kashan, Iran 4 General Practitioner, Kashan University of Medical Sciences, Kashan, Iran Background and Objective: Preeclampsia is one of the most critical complications of pregnancy observed in 2%-8% of all pregnancies. Severe preeclampsia has many maternal and neonatal complications that are more prevalent in early-onset preeclampsia. The present study aimed to determine the prevalence of maternal and neonatal outcomes of expectant management of severe preeclampsia before 34 weeks of gestation. Materials and Methods: In this retrospective descriptive study, the medical records of 55 mothers who had severe preeclampsia before 34 weeks of gestation and underwent expectant management and those of their neonates within 2014-2019 in Kashan, Iran, were reviewed. The information extracted from the medical records included maternal and neonatal demographic variables and outcomes. All data were analyzed in SPSS software (version 16) using descriptive and inferential statistics. The p-values of less than 0.05 were considered significant. Results: In this study, the rates of seizure, post-partum hemorrhage, intensive care unit admission, and platelet decline were 5.5%, 1.8%, 3.6%, and 7.3%, respectively. Moreover, 10.9% of mothers had renal failure, and therefore, elevated liver enzymes and hemolysis. Among the neonates, 44.7% and 12.7% of the cases had respiratory distress syndrome (RDS) and low Apgar scores, respectively. It was also revealed that 6.4% of the neonates had convulsions and pneumothorax (PTX), and neonatal mortality was observed in 6.4% of them. No significant relationship was observed between maternal outcomes and gestational age and between neonatal outcomes and the number of deliveries (P>0.05). However, renal failure outcomes had a significant relationship with the number of deliveries (P=0.023), meaning that all mothers with renal failure were nulliparous. It was found that gestational age had a significant relationship with the outcomes of neonatal death, low 5-minute Apgar score, low birth weight, RDS, and PTX (P<0.05); in other words, lower gestational age led to higher mentioned neonatal outcomes. Conclusion: Expectant management of early-onset preeclampsia was beneficial for neonates, and the implementation of regular and close monitoring in equipped centers would prevent the increase of maternal complications.http://sjh.umsha.ac.ir/article-1-2200-en.htmlexpectant managementpreeclampsiapregnancy outcome |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
Zohreh Tabasi Elahe Mesdaghinia Masoumeh Abedzadeh-Kalahroudi Hossein Akbari Mahsa Bandagi-Motlagh |
spellingShingle |
Zohreh Tabasi Elahe Mesdaghinia Masoumeh Abedzadeh-Kalahroudi Hossein Akbari Mahsa Bandagi-Motlagh Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia پزشکی بالینی ابن سینا expectant management preeclampsia pregnancy outcome |
author_facet |
Zohreh Tabasi Elahe Mesdaghinia Masoumeh Abedzadeh-Kalahroudi Hossein Akbari Mahsa Bandagi-Motlagh |
author_sort |
Zohreh Tabasi |
title |
Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia |
title_short |
Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia |
title_full |
Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia |
title_fullStr |
Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia |
title_full_unstemmed |
Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia |
title_sort |
maternal and neonatal outcomes in expectant management of early-onset severe preeclampsia |
publisher |
Hamadan University of Medical Sciences |
series |
پزشکی بالینی ابن سینا |
issn |
2588-722X 2588-7238 |
publishDate |
2021-06-01 |
description |
Background and Objective: Preeclampsia is one of the most critical complications of pregnancy observed in 2%-8% of all pregnancies. Severe preeclampsia has many maternal and neonatal complications that are more prevalent in early-onset preeclampsia. The present study aimed to determine the prevalence of maternal and neonatal outcomes of expectant management of severe preeclampsia before 34 weeks of gestation.
Materials and Methods: In this retrospective descriptive study, the medical records of 55 mothers who had severe preeclampsia before 34 weeks of gestation and underwent expectant management and those of their neonates within 2014-2019 in Kashan, Iran, were reviewed. The information extracted from the medical records included maternal and neonatal demographic variables and outcomes. All data were analyzed in SPSS software (version 16) using descriptive and inferential statistics. The p-values of less than 0.05 were considered significant.
Results: In this study, the rates of seizure, post-partum hemorrhage, intensive care unit admission, and platelet decline were 5.5%, 1.8%, 3.6%, and 7.3%, respectively. Moreover, 10.9% of mothers had renal failure, and therefore, elevated liver enzymes and hemolysis. Among the neonates, 44.7% and 12.7% of the cases had respiratory distress syndrome (RDS) and low Apgar scores, respectively. It was also revealed that 6.4% of the neonates had convulsions and pneumothorax (PTX), and neonatal mortality was observed in 6.4% of them. No significant relationship was observed between maternal outcomes and gestational age and between neonatal outcomes and the number of deliveries (P>0.05). However, renal failure outcomes had a significant relationship with the number of deliveries (P=0.023), meaning that all mothers with renal failure were nulliparous. It was found that gestational age had a significant relationship with the outcomes of neonatal death, low 5-minute Apgar score, low birth weight, RDS, and PTX (P<0.05); in other words, lower gestational age led to higher mentioned neonatal outcomes.
Conclusion: Expectant management of early-onset preeclampsia was beneficial for neonates, and the implementation of regular and close monitoring in equipped centers would prevent the increase of maternal complications. |
topic |
expectant management preeclampsia pregnancy outcome |
url |
http://sjh.umsha.ac.ir/article-1-2200-en.html |
work_keys_str_mv |
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