Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer
Gastric cancer is the forth most frequent malignancy and the second most common cause of cancer death worldwide. DNA methylation is the most studied epigenetic alteration, occurring through a methyl radical addition to the cytosine base adjacent to guanine. Many tumor genes are inactivated by DNA me...
Main Authors: | E.M. Lima, M.F. Leal, R.R. Burbano, A.S. Khayat, P.P. Assumpção, M.J. Bello, J.A. Rey, M.A.C. Smith, C. Casartelli |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
2008-06-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600017 |
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