Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats

Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats

The present study was undertaken to examine the inhibitory effect of crude leaves of Dodonaea viscosa (L) on lead acetate induced synthesis of glycoproteins and sialic acid in liver and plasma. Enhanced synthesis of glycoproteins (protein - bound hexose and protein - bound hexosamine) and sialic aci...

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Main Authors: D. Sivanesan, A. V. Veera Thamarai Selvi, R. Bhakyaraj, T. Arunachalam
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/294794
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spelling doaj-45dc7e7ef6d4459aa6143cd9996d84b32020-11-24T23:24:30ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102009-01-016372572810.1155/2009/294794Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in RatsD. Sivanesan0A. V. Veera Thamarai Selvi1R. Bhakyaraj2T. Arunachalam3Department of Biochemistry, J.J. College of Arts and Science, Pudukkottai-622 404, Tamil Nadu, IndiaDepartment of Biochemistry, J.J. College of Arts and Science, Pudukkottai-622 404, Tamil Nadu, IndiaPG and Research Department of Microbiology, J.J. College of Arts and Science, Pudukkottai-622 404, Tamil Nadu, IndiaDepartment of Chemistry, J.J. College of Arts and Science, Pudukkottai-622 404, Tamil Nadu, IndiaThe present study was undertaken to examine the inhibitory effect of crude leaves of Dodonaea viscosa (L) on lead acetate induced synthesis of glycoproteins and sialic acid in liver and plasma. Enhanced synthesis of glycoproteins (protein - bound hexose and protein - bound hexosamine) and sialic acid levels were found in liver and plasma of the lead acetate poisoned rats. Administration of crude leaves of D.viscosa (100 mg/100 g body weight P.O.) effectively suppressed the synthesis of glycoproteins and sialic acid in liver and thereby controlling the concentration in plasma. The results suggest that D.viscosa may exert its membrane protection effect by inhibiting the synthesis of glycoproteins and sialic acid induced by lead acetate.http://dx.doi.org/10.1155/2009/294794
collection DOAJ
language English
format Article
sources DOAJ
author D. Sivanesan
A. V. Veera Thamarai Selvi
R. Bhakyaraj
T. Arunachalam
spellingShingle D. Sivanesan
A. V. Veera Thamarai Selvi
R. Bhakyaraj
T. Arunachalam
Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats
E-Journal of Chemistry
author_facet D. Sivanesan
A. V. Veera Thamarai Selvi
R. Bhakyaraj
T. Arunachalam
author_sort D. Sivanesan
title Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats
title_short Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats
title_full Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats
title_fullStr Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats
title_full_unstemmed Protective Effect of Dodonaea viscosa (L) Against Lead Acetate Induced Altered Glycoprotein Profiles in Rats
title_sort protective effect of dodonaea viscosa (l) against lead acetate induced altered glycoprotein profiles in rats
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2009-01-01
description The present study was undertaken to examine the inhibitory effect of crude leaves of Dodonaea viscosa (L) on lead acetate induced synthesis of glycoproteins and sialic acid in liver and plasma. Enhanced synthesis of glycoproteins (protein - bound hexose and protein - bound hexosamine) and sialic acid levels were found in liver and plasma of the lead acetate poisoned rats. Administration of crude leaves of D.viscosa (100 mg/100 g body weight P.O.) effectively suppressed the synthesis of glycoproteins and sialic acid in liver and thereby controlling the concentration in plasma. The results suggest that D.viscosa may exert its membrane protection effect by inhibiting the synthesis of glycoproteins and sialic acid induced by lead acetate.
url http://dx.doi.org/10.1155/2009/294794
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AT avveerathamaraiselvi protectiveeffectofdodonaeaviscosalagainstleadacetateinducedalteredglycoproteinprofilesinrats
AT rbhakyaraj protectiveeffectofdodonaeaviscosalagainstleadacetateinducedalteredglycoproteinprofilesinrats
AT tarunachalam protectiveeffectofdodonaeaviscosalagainstleadacetateinducedalteredglycoproteinprofilesinrats
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