Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers

Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers

Background: Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effo...

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Main Authors: Sanne Skovgård Veidal, Anne-Christine Bay-Jensen, Gervais Tougas, Morten Asser Karsdal, Ben Vainer
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2010-0678
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spelling doaj-45e6cdc30a9443fea14d066573f9304d2020-11-24T23:01:07ZengHindawi LimitedDisease Markers0278-02401875-86302010-01-01281152810.3233/DMA-2010-0678Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New BiomarkersSanne Skovgård Veidal0Anne-Christine Bay-Jensen1Gervais Tougas2Morten Asser Karsdal3Ben Vainer4Department of Pharmacology, Nordic Bioscience, Herlev, DenmarkDepartment of Pharmacology, Nordic Bioscience, Herlev, DenmarkNovartis Pharma AG Translational Medicine, Basel, SwitzerlandDepartment of Pharmacology, Nordic Bioscience, Herlev, DenmarkDepartment of Pathology, Rigshospitalet, University of Copenhagen, DenmarkBackground: Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effort have been invested in finding alternative non-invasive approaches, these have not been sufficiently succesfull to replace biopsy assessment.http://dx.doi.org/10.3233/DMA-2010-0678
collection DOAJ
language English
format Article
sources DOAJ
author Sanne Skovgård Veidal
Anne-Christine Bay-Jensen
Gervais Tougas
Morten Asser Karsdal
Ben Vainer
spellingShingle Sanne Skovgård Veidal
Anne-Christine Bay-Jensen
Gervais Tougas
Morten Asser Karsdal
Ben Vainer
Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
Disease Markers
author_facet Sanne Skovgård Veidal
Anne-Christine Bay-Jensen
Gervais Tougas
Morten Asser Karsdal
Ben Vainer
author_sort Sanne Skovgård Veidal
title Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
title_short Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
title_full Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
title_fullStr Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
title_full_unstemmed Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-Epitope Approach in the Development of New Biomarkers
title_sort serum markers of liver fibrosis: combining the biped classification and the neo-epitope approach in the development of new biomarkers
publisher Hindawi Limited
series Disease Markers
issn 0278-0240
1875-8630
publishDate 2010-01-01
description Background: Fibrosis is a central histological feature of chronic liver diseases and is characterized by the accumulation and reorganization of the extracellular matrix. The gold standard for assessment of fibrosis is histological evaluation of a percutaneous liver biopsy. Albeit a considerable effort have been invested in finding alternative non-invasive approaches, these have not been sufficiently succesfull to replace biopsy assessment.
url http://dx.doi.org/10.3233/DMA-2010-0678
work_keys_str_mv AT sanneskovgardveidal serummarkersofliverfibrosiscombiningthebipedclassificationandtheneoepitopeapproachinthedevelopmentofnewbiomarkers
AT annechristinebayjensen serummarkersofliverfibrosiscombiningthebipedclassificationandtheneoepitopeapproachinthedevelopmentofnewbiomarkers
AT gervaistougas serummarkersofliverfibrosiscombiningthebipedclassificationandtheneoepitopeapproachinthedevelopmentofnewbiomarkers
AT mortenasserkarsdal serummarkersofliverfibrosiscombiningthebipedclassificationandtheneoepitopeapproachinthedevelopmentofnewbiomarkers
AT benvainer serummarkersofliverfibrosiscombiningthebipedclassificationandtheneoepitopeapproachinthedevelopmentofnewbiomarkers
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