Pathway-based analysis of a melanoma genome-wide association study: analysis of genes related to tumour-immunosuppression.

Pathway-based analysis of a melanoma genome-wide association study: analysis of genes related to tumour-immunosuppression.

Systemic immunosuppression is a risk factor for melanoma, and sunburn-induced immunosuppression is thought to be causal. Genes in immunosuppression pathways are therefore candidate melanoma-susceptibility genes. If variants within these genes individually have a small effect on disease risk, the ass...

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Bibliographic Details
Main Authors: Nils Schoof, Mark M Iles, D Timothy Bishop, Julia A Newton-Bishop, Jennifer H Barrett, Genomel Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3246481?pdf=render

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