Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial
Background. The present study aimed to assess and compare the pain perception and ulcer sizes before and after applying low-level laser therapy (LLLT) and Amlexanox + lidocaine. Methods. Twenty-six patients referring to the out-patient department of the institution and diagnosed with recurrent aphth...
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Tabriz University of Medical Sciences
2021-02-01
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doaj-46208c517fb74404946b87aee6be3ef32021-06-30T05:52:35ZengTabriz University of Medical SciencesJournal of Dental Research, Dental Clinics, Dental Prospects2008-210X2008-21182021-02-01151111510.34172/joddd.2021.003joddd-28064Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trialCharu Mohan Marya0Jiksha Mehlawat1Ruchi Nagpal2Sakshi Kataria3Pratibha Taneja4Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, IndiaDepartment of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, IndiaDepartment of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, IndiaDepartment of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, IndiaDepartment of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, IndiaBackground. The present study aimed to assess and compare the pain perception and ulcer sizes before and after applying low-level laser therapy (LLLT) and Amlexanox + lidocaine. Methods. Twenty-six patients referring to the out-patient department of the institution and diagnosed with recurrent aphthous ulcers (RAU) were assigned to two groups to receive either LLLT or Amlexanox + lidocaine. In group 1, the patients were provided with amlexanox + lidocaine to apply topically four times daily. In group 2, the patients underwent LLLT with no tissue contact in inward circular motions for two cycles for 30 seconds. This study was registered in "the Clinical Trials Registry- India" (CTRI), with the registration number CTRI/2019/09/028222. The data were analyzed with SPSS 16. Results. The intergroup comparison was performed using Mann-Whitney U test, and intragroup comparisons were made using Wilcoxon’s signed-rank test. The level of significance was set at P<0.05. The results showed that pain perception and ulcer size were significantly lower in group 2 subjects than group 1 subjects (P<0.05). Conclusion. LLLT was more effective than amlexanox + lidocaine in the management of RAU. It is a cost-effective therapy for treating RAU.https://joddd.tbzmed.ac.ir/PDF/joddd-15-11.pdfamlexanox and lidocainedrug therapylow-level laser therapyrandomized controlled trialrecurrent aphthous ulcers |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Charu Mohan Marya Jiksha Mehlawat Ruchi Nagpal Sakshi Kataria Pratibha Taneja |
spellingShingle |
Charu Mohan Marya Jiksha Mehlawat Ruchi Nagpal Sakshi Kataria Pratibha Taneja Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial Journal of Dental Research, Dental Clinics, Dental Prospects amlexanox and lidocaine drug therapy low-level laser therapy randomized controlled trial recurrent aphthous ulcers |
author_facet |
Charu Mohan Marya Jiksha Mehlawat Ruchi Nagpal Sakshi Kataria Pratibha Taneja |
author_sort |
Charu Mohan Marya |
title |
Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial |
title_short |
Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial |
title_full |
Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial |
title_fullStr |
Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial |
title_full_unstemmed |
Comparative assessment of low-level laser therapy (LLLT) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (RAUs): A randomized controlled trial |
title_sort |
comparative assessment of low-level laser therapy (lllt) vs. topical application of amlexanox + lidocaine to treat recurrent aphthous ulcers (raus): a randomized controlled trial |
publisher |
Tabriz University of Medical Sciences |
series |
Journal of Dental Research, Dental Clinics, Dental Prospects |
issn |
2008-210X 2008-2118 |
publishDate |
2021-02-01 |
description |
Background. The present study aimed to assess and compare the pain perception and ulcer sizes before and after applying low-level laser therapy (LLLT) and Amlexanox + lidocaine. Methods. Twenty-six patients referring to the out-patient department of the institution and diagnosed with recurrent aphthous ulcers (RAU) were assigned to two groups to receive either LLLT or Amlexanox + lidocaine. In group 1, the patients were provided with amlexanox + lidocaine to apply topically four times daily. In group 2, the patients underwent LLLT with no tissue contact in inward circular motions for two cycles for 30 seconds. This study was registered in "the Clinical Trials Registry- India" (CTRI), with the registration number CTRI/2019/09/028222. The data were analyzed with SPSS 16. Results. The intergroup comparison was performed using Mann-Whitney U test, and intragroup comparisons were made using Wilcoxon’s signed-rank test. The level of significance was set at P<0.05. The results showed that pain perception and ulcer size were significantly lower in group 2 subjects than group 1 subjects (P<0.05). Conclusion. LLLT was more effective than amlexanox + lidocaine in the management of RAU. It is a cost-effective therapy for treating RAU. |
topic |
amlexanox and lidocaine drug therapy low-level laser therapy randomized controlled trial recurrent aphthous ulcers |
url |
https://joddd.tbzmed.ac.ir/PDF/joddd-15-11.pdf |
work_keys_str_mv |
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