Application of CRISPR Tools for Variant Interpretation and Disease Modeling in Inherited Retinal Dystrophies

Application of CRISPR Tools for Variant Interpretation and Disease Modeling in Inherited Retinal Dystrophies

Inherited retinal dystrophies are an assorted group of rare diseases that collectively account for the major cause of visual impairment of genetic origin worldwide. Besides clinically, these vision loss disorders present a high genetic and allelic heterogeneity. To date, over 250 genes have been ass...

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Bibliographic Details
Main Authors:	Carla Fuster-García, Belén García-Bohórquez, Ana Rodríguez-Muñoz, José M. Millán, Gema García-García
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Genes
Subjects:	retinal diseases gene editing CRISPR cellular models animal models variants of unknown significance
Online Access:	https://www.mdpi.com/2073-4425/11/5/473

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