Imaging of cryptococcus neoformans infection in breasts: A case report

• Main Authors: Nguyen Thi Thu Ha, MD, Lai Thu Huong, MD, Dam Thuy Trang, MDPhD, Luu Hong Nhung, MD, Nguyen Thi Huyen, MD, Nguyen Quang Huy, MD, Do Duy Cuong, MDPhD, Vu Dang Luu, MDPhD
• Format: Article
• Language: English
• Published: Elsevier 2021-11-01
• Series: Radiology Case Reports
• Subjects: Immune thrombocytopenic purpura; cryptococcus neoformans; Breast infection; Case report
• Online Access: http://www.sciencedirect.com/science/article/pii/S1930043321005884

There have been few reports on the imaging characteristics of cryptococcus neoformans (C. neoformans) infection of the breast. Herein, we reported the imaging features of C. neoformans infection of the breast in a 41-year-old woman with immune thrombocytopenic purpura. Bilateral, diffuse, hyperechoic, and well-defined margin lesions were observed on breast ultrasounds. In addition, a global asymmetry in the left breast, and a focal asymmetry in the right breast were observed on mammograms. Breast fine needle aspiration and biopsy results revealed a C. neoformans infection. After 5 months of treatment with oral fluconazole and amphotericin B, the lesion on the right breast disappeared on repeated-breast ultrasounds.