Effects of Hypoxia in Intestinal Tumors on Immune Cell Behavior in the Tumor Microenvironment

Effects of Hypoxia in Intestinal Tumors on Immune Cell Behavior in the Tumor Microenvironment

BackgroundImbalanced nutritional supply and demand in the tumor microenvironment often leads to hypoxia. The subtle interaction between hypoxia and immune cell behavior plays an important role in tumor occurrence and development. However, the functional relationship between hypoxia and the tumor mic...

Full description

Bibliographic Details
Main Authors:	Luping Zhang, Shaokun Wang, Yachen Wang, Weidan Zhao, Yingli Zhang, Nan Zhang, Hong Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-03-01
Series:	Frontiers in Immunology
Subjects:	colorectal cancer hypoxia immune cell infiltration tumor microenvironment risk score
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.645320/full

Similar Items

Effects of Inflammation on the Immune Microenvironment in Gastric Cancer
by: Weidan Zhao, et al.
Published: (2021-07-01)

Identification of Immune Cell Infiltration and Immune-Related Genes in the Tumor Microenvironment of Glioblastomas
by: Sicong Huang, et al.
Published: (2020-10-01)

Screening and Validation of the Hypoxia-Related Signature of Evaluating Tumor Immune Microenvironment and Predicting Prognosis in Gastric Cancer
by: Jun-Peng Pei, et al.
Published: (2021-06-01)

Tumor Microenvironment Status Predicts the Efficacy of Postoperative Chemotherapy or Radiochemotherapy in Resected Gastric Cancer
by: Ran Duan, et al.
Published: (2021-01-01)

Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity
by: Bassam Janji, et al.
Published: (2018-04-01)

Identifying Hypoxia Characteristics to Stratify Prognosis and Assess the Tumor Immune Microenvironment in Renal Cell Carcinoma
by: Zhenan Zhang, et al.
Published: (2021-06-01)

Hypoxia-Driven Immune Escape in the Tumor Microenvironment
by: Alyssa Vito, et al.
Published: (2020-04-01)

The regulation of immune checkpoints by the hypoxic tumor microenvironment
by: Min Hu, et al.
Published: (2021-05-01)

Targeting hypoxia in the tumor microenvironment: a potential strategy to improve cancer immunotherapy
by: Bin Wang, et al.
Published: (2021-01-01)

Perspectives on Hypoxia Signaling in Tumor Stroma
by: Yuqing Zhang, et al.
Published: (2021-06-01)

A Robust Hypoxia Risk Score Predicts the Clinical Outcomes and Tumor Microenvironment Immune Characters in Bladder Cancer
by: Zhi Liu, et al.
Published: (2021-08-01)

Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment
by: Etienne D. Foucher, et al.
Published: (2018-05-01)

Characterization of Hypoxia Signature to Evaluate the Tumor Immune Microenvironment and Predict Prognosis in Glioma Groups
by: Wanzun Lin, et al.
Published: (2020-05-01)

MYD88 Is a Potential Prognostic Gene and Immune Signature of Tumor Microenvironment for Gliomas
by: Qinglong Guo, et al.
Published: (2021-04-01)

SERPINE1 associated with remodeling of the tumor microenvironment in colon cancer progression: a novel therapeutic target
by: Shaokun Wang, et al.
Published: (2021-07-01)

A 4-gene-based hypoxia signature is associated with tumor immune microenvironment and predicts the prognosis of pancreatic cancer patients
by: Jianfeng Ding, et al.
Published: (2021-04-01)

Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of colorectal cancer
by: Penglei Ge, et al.
Published: (2019-10-01)

Tumor Immune Microenvironment Characterization Identifies Prognosis and Immunotherapy-Related Gene Signatures in Melanoma
by: Dan Liu, et al.
Published: (2021-05-01)

Identification of Immune-Related Prognostic Biomarkers Based on the Tumor Microenvironment in 20 Malignant Tumor Types With Poor Prognosis
by: Yu Liu, et al.
Published: (2020-07-01)

An Integrative Pan-Cancer Analysis Revealing LCN2 as an Oncogenic Immune Protein in Tumor Microenvironment
by: Wen-Xiu Xu, et al.
Published: (2020-12-01)

Prognostic Gene Expression, Stemness and Immune Microenvironment in Pediatric Tumors
by: David Stahl, et al.
Published: (2021-02-01)

Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment
by: Ellen N. Scott, et al.
Published: (2021-06-01)

Hypoxia-Related lncRNA Correlates With Prognosis and Immune Microenvironment in Lower-Grade Glioma
by: Shengchao Xu, et al.
Published: (2021-09-01)

Prognostic Value of Immune-Related Genes in the Tumor Microenvironment of Bladder Cancer
by: Faping Li, et al.
Published: (2020-07-01)

TGFβ1: An Indicator for Tumor Immune Microenvironment of Colon Cancer From a Comprehensive Analysis of TCGA
by: Jinyan Wang, et al.
Published: (2021-04-01)

Tumor Dormancy and Interplay with Hypoxic Tumor Microenvironment
by: Elena Butturini, et al.
Published: (2019-09-01)

Identification and immunoprofiling of key prognostic genes in the tumor microenvironment of hepatocellular carcinoma
by: Tianbing Wang, et al.
Published: (2021-01-01)

Starved and asphyxiated: how can CD8+T cells within a tumor microenvironment prevent tumor progression
by: Ying eZhang, et al.
Published: (2016-02-01)

Regulation of Ovarian Cancer Prognosis by Immune Cells in the Tumor Microenvironment
by: Maureen L. Drakes, et al.
Published: (2018-09-01)

Prognostic Value of Genes and Immune Infiltration in Prostate Tumor Microenvironment
by: Wenguo Sun, et al.
Published: (2020-10-01)

Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models
by: Somshuvra Bhattacharya, et al.
Published: (2020-05-01)

m6A Regulator-Associated Modification Patterns and Immune Infiltration of the Tumor Microenvironment in Hepatocarcinoma
by: Jianhao Li, et al.
Published: (2021-07-01)

CXCL10 is a Tumor Microenvironment and Immune Infiltration Related Prognostic Biomarker in Pancreatic Adenocarcinoma
by: Huimin Huang, et al.
Published: (2021-02-01)

The Tumor Microenvironment in Colorectal Cancer Therapy
by: Leire Pedrosa, et al.
Published: (2019-08-01)

CD52 Is a Prognostic Biomarker and Associated With Tumor Microenvironment in Breast Cancer
by: Jianxin Wang, et al.
Published: (2020-11-01)

Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of esophageal squamous cell carcinoma
by: Mingdi Liu, et al.
Published: (2021-03-01)

Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment
by: Li Yang, et al.
Published: (2019-11-01)

Tumor immune infiltration estimated from gene expression profiles predicts colorectal cancer relapse
by: Yasmin Kamal, et al.
Published: (2021-01-01)

Immune Landscape of the Tumor Microenvironment Identifies Prognostic Gene Signature CD4/CD68/CSF1R in Osteosarcoma
by: Yi-jiang Song, et al.
Published: (2020-07-01)

Role of hypoxia in cancer therapy by regulating the tumor microenvironment
by: Xinming Jing, et al.
Published: (2019-11-01)