The Effect of Residual Renal Function on Clinical and Laboratory Parameters in Peritoneal Dialysis Patients

• Main Authors: İbrahim Halil Düşünceli, Metin Ergül, Necmi Eren, Betül Gönüllü Kalender, Erkan Dervişoğlu
• Format: Article
• Language: English
• Published: Galenos Yayinevi 2020-09-01
• Series: Haseki Tıp Bülteni
• Subjects: albumin; hemoglobin; peritoneal dialysis; residual renal function
• Online Access: http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-residual-renal-function-on-clinical-/40230
• ISSN: 1302-0072; 2147-2688

Aim:To evaluate the effects of residual renal function (RRF) on anemia treatment, phosphorus control and nutritional parameters in peritoneal dialysis (PD) patients.Methods:PD patients were retrospectively analyzed. Besides anthropometric measurements, biochemical measurements, such as residual glomerular filtration rate (rGFR), normalized protein catabolic rate (nPCR), hemoglobin (Hb), serum albumin, calcium, phosphorus, ferritin, parathormone and C-reactive protein levels were recorded.Results:One hundred and fifteen patients (52 females, 63 males; mean age: 56.0±13.2 years 20-83 years) receiving PD treatment were analyzed. The patients were divided into two groups according to presence or absence of RRF (n=75 and n=40, respectively). Patients with RRF had higher body weight (80±14 kg vs 68±13 kg; p<0.001), body mass index (29±5 kg/m² vs 25±5 kg/m²; p=0.009) and serum albumin level (3.6±0.5 vs 3.4±0.5 g/dL; p=0.027]. Patients with RRF had lower erythropoietin [29 (39%), vs. 34 (85%); p<0.001), sevelamer [17 (22.7%) vs 24 (60%); p<0.001] and calcimimetic [9 (12%) vs 14 (35%); p=0.007] usage rates and lower ferritin [159 (88-259) ng/mL vs 323 (170-495) ng/mL; p=0.001] level. rGFR was found to be positively correlated with Hb (r=0.274; p=0.017) and nPCR in patients with RRF (r=0.251; p=0.030).Conclusion:In our study, the positive effects of RRF on the treatment of anemia, phosphorus control and nutritional status in PD patients were shown.