An Evolving Role for DEPTOR in Tumor Development and Progression
Deregulation of the mammalian target of rapamycin (mTOR) signaling pathway has been found in a variety of human cancers. However, the exact molecular mechanism how the mTOR signaling pathway is regulated remains largely elusive. Recently, DEPTOR was identified as an endogenous mTOR inhibitor that c...
Main Authors: | Zhiwei Wang, Jiateng Zhong, Hiroyuki Inuzuka, Daming Gao, Shavali Shaik, Fazlul H. Sarkar, Wenyi Wei |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-05-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558612800121 |
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