Physically-induced cytoskeleton remodeling of cells in three-dimensional culture.

Characterizing how cells in three-dimensional (3D) environments or natural tissues respond to biophysical stimuli is a longstanding challenge in biology and tissue engineering. We demonstrate a strategy to monitor morphological and mechanical responses of contractile fibroblasts in a 3D environment....

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Bibliographic Details
Main Authors: Sheng-Lin Lee, Ali Nekouzadeh, Boyd Butler, Kenneth M Pryse, William B McConnaughey, Adam C Nathan, Wesley R Legant, Pascal M Schaefer, Robert B Pless, Elliot L Elson, Guy M Genin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3531413?pdf=render

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