Physically-induced cytoskeleton remodeling of cells in three-dimensional culture.
Characterizing how cells in three-dimensional (3D) environments or natural tissues respond to biophysical stimuli is a longstanding challenge in biology and tissue engineering. We demonstrate a strategy to monitor morphological and mechanical responses of contractile fibroblasts in a 3D environment....
Main Authors: | Sheng-Lin Lee, Ali Nekouzadeh, Boyd Butler, Kenneth M Pryse, William B McConnaughey, Adam C Nathan, Wesley R Legant, Pascal M Schaefer, Robert B Pless, Elliot L Elson, Guy M Genin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3531413?pdf=render |
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