Cumulative live birth rate according to the number of receiving governmental subsidies for assisted reproductive technology in Saitama Prefecture, Japan: A retrospective study using individual data for governmental subsidies

• Main Authors: Seung Chik Jwa, Osamu Ishihara, Akira Kuwahara, Kazuki Saito, Hidekazu Saito, Yukihiro Terada, Yasuki Kobayashi, Eri Maeda
• Format: Article
• Language: English
• Published: Wiley 2021-10-01
• Series: Reproductive Medicine and Biology
• Subjects: assisted reproductive technology; embryo transfer; intracytoplasmic sperm injection; in‐vitro fertilization; pregnancy rate
• Online Access: https://doi.org/10.1002/rmb2.12397
• ISSN: 1445-5781; 1447-0578

Abstract Purpose We investigated the cumulative live birth rate (CLBR) in women receiving governmental subsidies for assisted reproductive technology (ART) in Saitama Prefecture, Japan. Methods Women who applied for subsidies from Saitama Prefectural Government for the first time in 2016 were enrolled and followed up until the end of 2017. Treatment information, including live birth, was obtained from the Japanese ART registry by linking it with unique identification numbers for treatment. Patients’ factors associated with having a live birth were investigated. Results Of 1,072 women (2,513 applications), 495 (46.2%) had a live birth with 8 (1.6%) twin pregnancies. The CLBR over six subsidized cycles was 53.7% for women aged <40 years, and 17.2% over three subsidized cycles for women 40‐42 years; highest among women <35 years (58.4%), followed by those aged 35‐39 years (49.3%). Multivariate analysis revealed patient age as the only independent factor for having a live birth. Conclusions The CLBR of women receiving subsidies for ART was greatest in women aged <35 years. Effective policies for promoting ART among younger couples who seek infertility treatment are essential.