Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles
Pure hydroxyapatite (HA) and hydroxyapatite decorated with silver (HA@Ag) nanoparticles were synthesized and characterized. The antifungal effect of HA@Ag nanoparticles in a distilled water solution was evaluated against Candida albicans. The origin of the antifungal activity of the HA@Ag is also di...
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Series: | Journal of Nanomaterials |
Online Access: | http://dx.doi.org/10.1155/2013/174398 |
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doaj-47082150ce374b1785c203d2d0eeaa4b2020-11-24T20:49:23ZengHindawi LimitedJournal of Nanomaterials1687-41101687-41292013-01-01201310.1155/2013/174398174398Antifungal Applications of Ag-Decorated Hydroxyapatite NanoparticlesC. A. Zamperini0R. S. André1V. M. Longo2E. G. Mima3C. E. Vergani4A. L. Machado5J. A. Varela6E. Longo7LIEC, UNESP-Univ Estadual Paulista, P.O. Box 355, 14801-907 Araraquara, SP, BrazilLIEC, CMDMC, Department of Chemistry, Universidade Federal de São Carlos (UFSCar), 13565-905, São Carlos, SP, BrazilLIEC, UNESP-Univ Estadual Paulista, P.O. Box 355, 14801-907 Araraquara, SP, BrazilDepartment of Dental Materials and Prosthodontics, Araraquara Dental School, UNESP-Univ Estadual Paulista, 14801-903 Araraquara, SP, BrazilDepartment of Dental Materials and Prosthodontics, Araraquara Dental School, UNESP-Univ Estadual Paulista, 14801-903 Araraquara, SP, BrazilDepartment of Dental Materials and Prosthodontics, Araraquara Dental School, UNESP-Univ Estadual Paulista, 14801-903 Araraquara, SP, BrazilLIEC, UNESP-Univ Estadual Paulista, P.O. Box 355, 14801-907 Araraquara, SP, BrazilLIEC, UNESP-Univ Estadual Paulista, P.O. Box 355, 14801-907 Araraquara, SP, BrazilPure hydroxyapatite (HA) and hydroxyapatite decorated with silver (HA@Ag) nanoparticles were synthesized and characterized. The antifungal effect of HA@Ag nanoparticles in a distilled water solution was evaluated against Candida albicans. The origin of the antifungal activity of the HA@Ag is also discussed. The results obtained showed that the HA nanorod morphology remained the same with Ag ions decorations on the HA structure which were deposited in the form of nanospheres. Interaction where occurred between the structure and its defect density variation in the interfacial HA@Ag and intrafacial HA region with the fungal medium resulted in antifungal activity. The reaction mechanisms involved oxygen and water adsorption which formed an active complex cluster. The decomposition and desorption of the final products as well as the electron/hole recombination process have an important role in fungicidal effects.http://dx.doi.org/10.1155/2013/174398 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
C. A. Zamperini R. S. André V. M. Longo E. G. Mima C. E. Vergani A. L. Machado J. A. Varela E. Longo |
spellingShingle |
C. A. Zamperini R. S. André V. M. Longo E. G. Mima C. E. Vergani A. L. Machado J. A. Varela E. Longo Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles Journal of Nanomaterials |
author_facet |
C. A. Zamperini R. S. André V. M. Longo E. G. Mima C. E. Vergani A. L. Machado J. A. Varela E. Longo |
author_sort |
C. A. Zamperini |
title |
Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles |
title_short |
Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles |
title_full |
Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles |
title_fullStr |
Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles |
title_full_unstemmed |
Antifungal Applications of Ag-Decorated Hydroxyapatite Nanoparticles |
title_sort |
antifungal applications of ag-decorated hydroxyapatite nanoparticles |
publisher |
Hindawi Limited |
series |
Journal of Nanomaterials |
issn |
1687-4110 1687-4129 |
publishDate |
2013-01-01 |
description |
Pure hydroxyapatite (HA) and hydroxyapatite decorated with silver (HA@Ag) nanoparticles were synthesized and characterized. The antifungal effect of HA@Ag nanoparticles in a distilled water solution was evaluated against Candida albicans. The origin of the antifungal activity of the HA@Ag is also discussed. The results obtained showed that the HA nanorod morphology remained the same with Ag ions decorations on the HA structure which were deposited in the form of nanospheres. Interaction where occurred between the structure and its defect density variation in the interfacial HA@Ag and intrafacial HA region with the fungal medium resulted in antifungal activity. The reaction mechanisms involved oxygen and water adsorption which formed an active complex cluster. The decomposition and desorption of the final products as well as the electron/hole recombination process have an important role in fungicidal effects. |
url |
http://dx.doi.org/10.1155/2013/174398 |
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