Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014
Background and Objectives: tuberculosis remains a relevant public health problem and the cure of diagnosed cases is a strategy to reduce high morbidity and mortality. The objective of our study is to identify factors associated with death due to tuberculosis and treatment default in patients diagnos...
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Universidade de Santa Cruz do Sul
2018-04-01
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doaj-4713fdbc2f44402cb6579f5034351d7a2020-11-24T21:15:33ZporUniversidade de Santa Cruz do SulRevista de Epidemiologia e Controle de Infecção2238-33602018-04-018215015810.17058/reci.v8i2.106755104Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014Alessandra Gonçalves Lisbôa Pereira0Claudia Caminha Escosteguy1Juliana Brito Gonçalves2Marcio Renan Vinícius Espínula Marques3Catarina Medeiros Brasil4Maria Carolina Souza da Silva5Hospital Federal dos Servidores do Estado, Rio de Janeiro, RJServiço de Epidemiologia do Hospital Federal dos Servidores do Estado, Ministério da Saúde, Rio de Janeiro, RJInstituto de Estudos em Saúde Coletiva da Universidade Federal do Rio de Janeiro, Rio de Janeiro-RJServiço de Epidemiologia do Hospital Federal dos Servidores do Estado, Ministério da Saúde, Rio de Janeiro-RJFaculdade de Medicina da Universidade Estácio de Sá, Rio de Janeiro-RJFaculdade de Medicina da Universidade Estácio de Sá, Rio de Janeiro-RJBackground and Objectives: tuberculosis remains a relevant public health problem and the cure of diagnosed cases is a strategy to reduce high morbidity and mortality. The objective of our study is to identify factors associated with death due to tuberculosis and treatment default in patients diagnosed in the HFSE from 2007 to 2014. Method: we conducted an observational, analytical study of all 670 confirmed cases reported in this period at the local SINAN reporting base, whose outcome was registered as cure (383), tuberculosis death (159) or default (128). This system is fed from a standardized epidemiological investigation sheet containing socio-demographic and clinical variables. Statistical analysis involved variables available in SINAN and considered as unfavorable outcome that composed by death or default. Variables with high odds ratios in bivariate analysis and/or clinical relevance were considered for inclusion in a logistic regression model. As a measure of association for analysis of factors associated with unfavorable outcome versus cure, odds ratios and their 95% confidence intervals were estimated. Results: the final model identified as statistically associated with an unfavorable outcome: age ≥60 years, non-white race/color, history of previous treatment for tuberculosis, or unknown history of previous treatment, positive anti-HIV test, pulmonary form and presence of severe extrapulmonary forms. Conclusion: the results confirm the need to invest in policies that guarantee access and fair care to patients, especially those with conditions that predispose to default and severe forms.https://online.unisc.br/seer/index.php/epidemiologia/article/view/10675 |
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DOAJ |
language |
Portuguese |
format |
Article |
sources |
DOAJ |
author |
Alessandra Gonçalves Lisbôa Pereira Claudia Caminha Escosteguy Juliana Brito Gonçalves Marcio Renan Vinícius Espínula Marques Catarina Medeiros Brasil Maria Carolina Souza da Silva |
spellingShingle |
Alessandra Gonçalves Lisbôa Pereira Claudia Caminha Escosteguy Juliana Brito Gonçalves Marcio Renan Vinícius Espínula Marques Catarina Medeiros Brasil Maria Carolina Souza da Silva Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014 Revista de Epidemiologia e Controle de Infecção |
author_facet |
Alessandra Gonçalves Lisbôa Pereira Claudia Caminha Escosteguy Juliana Brito Gonçalves Marcio Renan Vinícius Espínula Marques Catarina Medeiros Brasil Maria Carolina Souza da Silva |
author_sort |
Alessandra Gonçalves Lisbôa Pereira |
title |
Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014 |
title_short |
Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014 |
title_full |
Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014 |
title_fullStr |
Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014 |
title_full_unstemmed |
Factors associated with death from tuberculosis and treatment default in a general hospital in the city of Rio de Janeiro, 2007 to 2014 |
title_sort |
factors associated with death from tuberculosis and treatment default in a general hospital in the city of rio de janeiro, 2007 to 2014 |
publisher |
Universidade de Santa Cruz do Sul |
series |
Revista de Epidemiologia e Controle de Infecção |
issn |
2238-3360 |
publishDate |
2018-04-01 |
description |
Background and Objectives: tuberculosis remains a relevant public health problem and the cure of diagnosed cases is a strategy to reduce high morbidity and mortality. The objective of our study is to identify factors associated with death due to tuberculosis and treatment default in patients diagnosed in the HFSE from 2007 to 2014. Method: we conducted an observational, analytical study of all 670 confirmed
cases reported in this period at the local SINAN reporting base, whose outcome was registered as cure (383), tuberculosis death (159) or default (128). This system is fed from a standardized epidemiological investigation sheet containing socio-demographic and clinical variables. Statistical analysis involved variables available in SINAN and considered as unfavorable outcome that composed by death or default. Variables with high odds ratios in bivariate analysis and/or clinical relevance were considered for inclusion in a logistic regression model. As a measure of association for analysis of factors associated with unfavorable outcome versus cure, odds ratios and their 95% confidence intervals were estimated. Results: the final model identified as statistically associated with an unfavorable outcome: age ≥60 years, non-white race/color, history of previous treatment for tuberculosis, or unknown history of previous treatment, positive anti-HIV test, pulmonary form and presence of severe extrapulmonary forms. Conclusion: the results confirm the need to invest in policies that guarantee access and fair care to patients, especially those with conditions that predispose to default and severe forms. |
url |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/10675 |
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