CD40L and IL-4 stimulation of acute lymphoblastic leukemia cells results in upregulation of mRNA level of FLICE--an important component of apoptosis.

The use of cancer vaccines based on dendritic cells (DC) presenting tumor antigens can be a promising tool in the treatment of leukemia. The functional characteristics of leukemia derived DC is still to be elucidated. CD40 promotes survival, proliferation and differentiation of normal B cells. CD40...

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Main Authors: Radosław Jaworowski, Igor Olejnik, Tomasz Szczepalński, Andrzej Kołtan, Iwona Malinowska, Maryna Krawczuk-Rybak, Anna Stasiak-Barmuta, Elibieta Iłendo, Oksana Kowalczuk, Włodzimierz łuczyński, Lech Chyczewski, Michał Matysiak, Mariusz Wysocki, Danuta Sońta-Jakimczyk, Maria Wieczorek
Format: Article
Language:English
Published: Via Medica 2007-03-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4545