Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane
Purpose: To describe the first reported case of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) associated with a remote choroidal neovascular membrane (CNVM). Observations: A 19-month-old girl with a normal prenatal and infantile history presented with esotropia of the left...
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doaj-473bfc2eb578457bb35eade520d58b602020-12-21T04:47:19ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362020-12-0120100954Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membraneThomas A. Lazzarini0Hasenin Al-khersan1Nimesh A. Patel2Jonathan F. Russell3Kenneth C. Fan4Giselle De Oliveira5Catherin I. Negron6Elias Mavrofrides7Audina M. Berrocal8Bascom Palmer Eye Institute, Miami, FL, USABascom Palmer Eye Institute, Miami, FL, USABascom Palmer Eye Institute, Miami, FL, USABascom Palmer Eye Institute, Miami, FL, USABascom Palmer Eye Institute, Miami, FL, USABascom Palmer Eye Institute, Miami, FL, USABascom Palmer Eye Institute, Miami, FL, USAOrlando Retina Institute, Orlando, FL, USABascom Palmer Eye Institute, Miami, FL, USA; Corresponding author. Bascom Palmer Eye Institute 900 NW 17th St Miami, FL, 33136, USA.Purpose: To describe the first reported case of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) associated with a remote choroidal neovascular membrane (CNVM). Observations: A 19-month-old girl with a normal prenatal and infantile history presented with esotropia of the left eye. Fundus examination demonstrated a large, elevated, charcoal-colored lesion in the nasal equatorial retina. There was dragging of the nasal retinal vessels and a retinal fold, presumed to have resulted from nasal traction from the lesion. There was also subretinal hemorrhage in the peripapillary macula. Multimodal imaging demonstrated a peripapillary choroidal neovascular membrane (CNVM) underlying the retinal fold. There was no leakage within the tumor or secondary retinal neovascularization. Examination of the fellow eye was unremarkable. The patient was diagnosed with peripheral CHRRPE with associated peripapillary CNVM. She was treated with serial intravitreal bevacizumab to the affected eye which resulted in a reduction in leakage from the CNVM and resolution of the subretinal hemorrhage. The CHRRPE remained stable on follow-up. Conclusions: Peripheral CHRRPE can rarely be associated with a remote CNVM.http://www.sciencedirect.com/science/article/pii/S2451993620302693Combined hamartoma of retina and retinal pigment epitheliumSecondary choroidal neovascularizationChoroidal neovascular membraneRetinaPediatric retinaBevacizumab |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Thomas A. Lazzarini Hasenin Al-khersan Nimesh A. Patel Jonathan F. Russell Kenneth C. Fan Giselle De Oliveira Catherin I. Negron Elias Mavrofrides Audina M. Berrocal |
spellingShingle |
Thomas A. Lazzarini Hasenin Al-khersan Nimesh A. Patel Jonathan F. Russell Kenneth C. Fan Giselle De Oliveira Catherin I. Negron Elias Mavrofrides Audina M. Berrocal Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane American Journal of Ophthalmology Case Reports Combined hamartoma of retina and retinal pigment epithelium Secondary choroidal neovascularization Choroidal neovascular membrane Retina Pediatric retina Bevacizumab |
author_facet |
Thomas A. Lazzarini Hasenin Al-khersan Nimesh A. Patel Jonathan F. Russell Kenneth C. Fan Giselle De Oliveira Catherin I. Negron Elias Mavrofrides Audina M. Berrocal |
author_sort |
Thomas A. Lazzarini |
title |
Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane |
title_short |
Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane |
title_full |
Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane |
title_fullStr |
Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane |
title_full_unstemmed |
Peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane |
title_sort |
peripheral combined hamartoma of the retina and retinal pigment epithelium with remote peripapillary choroidal neovascular membrane |
publisher |
Elsevier |
series |
American Journal of Ophthalmology Case Reports |
issn |
2451-9936 |
publishDate |
2020-12-01 |
description |
Purpose: To describe the first reported case of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) associated with a remote choroidal neovascular membrane (CNVM). Observations: A 19-month-old girl with a normal prenatal and infantile history presented with esotropia of the left eye. Fundus examination demonstrated a large, elevated, charcoal-colored lesion in the nasal equatorial retina. There was dragging of the nasal retinal vessels and a retinal fold, presumed to have resulted from nasal traction from the lesion. There was also subretinal hemorrhage in the peripapillary macula. Multimodal imaging demonstrated a peripapillary choroidal neovascular membrane (CNVM) underlying the retinal fold. There was no leakage within the tumor or secondary retinal neovascularization. Examination of the fellow eye was unremarkable. The patient was diagnosed with peripheral CHRRPE with associated peripapillary CNVM. She was treated with serial intravitreal bevacizumab to the affected eye which resulted in a reduction in leakage from the CNVM and resolution of the subretinal hemorrhage. The CHRRPE remained stable on follow-up. Conclusions: Peripheral CHRRPE can rarely be associated with a remote CNVM. |
topic |
Combined hamartoma of retina and retinal pigment epithelium Secondary choroidal neovascularization Choroidal neovascular membrane Retina Pediatric retina Bevacizumab |
url |
http://www.sciencedirect.com/science/article/pii/S2451993620302693 |
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