Kadar TNF-α dan IL-1β cairan sulkus gingiva setelah pemasangan mahkota akrilik

• Main Authors: Edy Machmud, Roswita Roswita
• Format: Article
• Language: English
• Published: Hasanuddin University 2007-04-01
• Series: Journal of Dentomaxillofacial Science
• Subjects: acrylic jacket crown, gingival crevicular fluid, TNF-α, IL-1β
• Online Access: http://jdmfs.org/index.php/jdmfs/article/view/138

Cervical margin of fixed denture either jacket crown or bridge, is usually placed subgingivally for the natural look, however this can sometimes cause gingival inflammation. Moreover, if the restoration material is acrylic, it sometimes can irritate oral tissue. The aim of this study was to investigate the effect of acrylic, used as fixed denture material, to gingival tissue reaction. This was an experimental study, using pre and post test of 5 acrylic jacket crowns, made to patients in the Prosthodontic Department, Dental Hospital of Hasanuddin University. Gingival crevicular fluid (GCF) was collected before preparation, and three weeks after insertion of the jacket crowns, then pro-inflammatory cytokines; TNF-α and IL-1β were examined. The results analyzed by Wilcoxon sign rank test (p<0.05). The results showed the elevation of TNF-α and IL1β concentration after acrylic jacket crown insertion compare with the concentration before preparation. The conclusion of this study is acrylic restoration material may cause gingival inflammation.