tmap: an integrative framework based on topological data analysis for population-scale microbiome stratification and association studies

Abstract Untangling the complex variations of microbiome associated with large-scale host phenotypes or environment types challenges the currently available analytic methods. Here, we present tmap, an integrative framework based on topological data analysis for population-scale microbiome stratifica...

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Bibliographic Details
Main Authors: Tianhua Liao, Yuchen Wei, Mingjing Luo, Guo-Ping Zhao, Haokui Zhou
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-019-1871-4