Differentially expressed microRNAs in colorectal cancer metastasis

Tumor metastasis continues to be the most significant contributor to cancer related mortality, and although several studies have examined expression profiles emanating from patients with metastatic disease, very little information is available about signatures that differentiate metastatic lesions f...

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Bibliographic Details
Main Authors: Mohammed Abba, Axel Benner, Nitin Patil, Oliver Heil, Heike Allgayer
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015001750
Description
Summary:Tumor metastasis continues to be the most significant contributor to cancer related mortality, and although several studies have examined expression profiles emanating from patients with metastatic disease, very little information is available about signatures that differentiate metastatic lesions from primary tumors and associated normal tissues, largely because such matched tissue sample series are rare. This study was specifically designed to identify the metastasis relevant microRNAs in colorectal cancer and characterize microRNAs that modulate the metastatic phenotype. Here we describe in detail how the data, deposited in the Gene Expression Omnibus (GEO) with the accession number GSE54088, was generated including the basic analysis as contained in the manuscript published in Cancer Research with the PMID 26069251.
ISSN:2213-5960