A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans.
In Caenorhabditis elegans and Drosophila melanogaster, the aging of the soma is influenced by the germline. When germline-stem cells are removed, aging slows and lifespan is increased. The mechanism by which somatic tissues respond to loss of the germline is not well-understood. Surprisingly, we hav...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-09-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2729384?pdf=render |