A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans.
In Caenorhabditis elegans and Drosophila melanogaster, the aging of the soma is influenced by the germline. When germline-stem cells are removed, aging slows and lifespan is increased. The mechanism by which somatic tissues respond to loss of the germline is not well-understood. Surprisingly, we hav...
Main Authors: | Arjumand Ghazi, Sivan Henis-Korenblit, Cynthia Kenyon |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-09-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2729384?pdf=render |
Similar Items
-
Auxin treatment increases lifespan in Caenorhabditis elegans
by: Julia A. Loose, et al.
Published: (2021-05-01) -
4-Hydroxybenzoic acid-mediated lifespan extension in Caenorhabditis elegans
by: Dae Keun Kim, et al.
Published: (2014-03-01) -
Lifespan extension induced by caffeine in Caenorhabditis elegans is partially dependent on adenosine signaling
by: Jessika Cristina Bridi, et al.
Published: (2015-12-01) -
Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16
by: Wim Wätjen, et al.
Published: (2013-06-01) -
Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans
by: Hanmei Li, et al.
Published: (2019-03-01)