Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis
Abstract Objective The aim of this study was to compare the safety feasibility and safety feasibility of non-intubated (NIVATS) and intubated video-assisted thoracoscopic surgeries (IVATS) during major pulmonary resections. Methods A meta-analysis of eight studies was conducted to compare the real e...
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Online Access: | https://doi.org/10.1186/s12957-021-02181-x |
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doaj-47678413f1f649218dfef933d4329da82021-03-28T11:21:18ZengBMCWorld Journal of Surgical Oncology1477-78192021-03-0119111010.1186/s12957-021-02181-xComparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysisWenfei Xue0Guochen Duan1Xiaopeng Zhang2Hua Zhang3Qingtao Zhao4Zhifei Xin5Jie He6Department of Thoracic Surgery, Hebei Province General HospitalDepartment of Thoracic Surgery, Hebei Province General HospitalDepartment of Thoracic Surgery, Hebei Province General HospitalDepartment of Thoracic Surgery, Hebei Province General HospitalDepartment of Thoracic Surgery, Hebei Province General HospitalDepartment of Thoracic Surgery, Hebei Province General HospitalDepartment of Thoracic Surgery, Hebei Province General HospitalAbstract Objective The aim of this study was to compare the safety feasibility and safety feasibility of non-intubated (NIVATS) and intubated video-assisted thoracoscopic surgeries (IVATS) during major pulmonary resections. Methods A meta-analysis of eight studies was conducted to compare the real effects of two lobectomy or segmentectomy approaches during major pulmonary resections. Results Results showed that the patients using NIVATS had a greatly shorter hospital stay and chest-tube placement time (weighted mean difference (WMD): − 1.04 days; 95% CI − 1.50 to − 0.58; P < 0.01) WMD − 0.71 days; 95% confidence interval (CI), − 1.08 to − 0.34; P < 0.01, respectively) while compared to those with IVATS. There were no significant differences in postoperative complication rate, surgical duration, and the number of dissected lymph nodes. However, through the analysis of highly selected patients with lung cancer in early stage, the rate of postoperative complication in the NIVATS group was lower than that in the IVATS group [odds ratio (OR) 0.44; 95% CI 0.21–0.92; P = 0.03, I 2 = 0%]. Conclusions Although the comparable postoperative complication rate was observed for major thoracic surgery in two surgical procedures, the NIVATS method could significantly shorten the hospitalized stay and chest-tube placement time compared with IVATS. Therefore, for highly selected patients, NIVATS is regarded as a safe and technically feasible procedure for major thoracic surgery. The assessment of the safety and feasibility for patients undergoing NIVATS needs further multi-center prospective clinical trials.https://doi.org/10.1186/s12957-021-02181-xThoracic surgeryNon-intubated anesthesiaMajor lung resectionLobectomySegmentectomySpontaneous breathing |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wenfei Xue Guochen Duan Xiaopeng Zhang Hua Zhang Qingtao Zhao Zhifei Xin Jie He |
spellingShingle |
Wenfei Xue Guochen Duan Xiaopeng Zhang Hua Zhang Qingtao Zhao Zhifei Xin Jie He Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis World Journal of Surgical Oncology Thoracic surgery Non-intubated anesthesia Major lung resection Lobectomy Segmentectomy Spontaneous breathing |
author_facet |
Wenfei Xue Guochen Duan Xiaopeng Zhang Hua Zhang Qingtao Zhao Zhifei Xin Jie He |
author_sort |
Wenfei Xue |
title |
Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis |
title_short |
Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis |
title_full |
Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis |
title_fullStr |
Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis |
title_full_unstemmed |
Comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis |
title_sort |
comparison of non-intubated and intubated video-assisted thoracoscopic surgeries of major pulmonary resections for lung cancer—a meta-analysis |
publisher |
BMC |
series |
World Journal of Surgical Oncology |
issn |
1477-7819 |
publishDate |
2021-03-01 |
description |
Abstract Objective The aim of this study was to compare the safety feasibility and safety feasibility of non-intubated (NIVATS) and intubated video-assisted thoracoscopic surgeries (IVATS) during major pulmonary resections. Methods A meta-analysis of eight studies was conducted to compare the real effects of two lobectomy or segmentectomy approaches during major pulmonary resections. Results Results showed that the patients using NIVATS had a greatly shorter hospital stay and chest-tube placement time (weighted mean difference (WMD): − 1.04 days; 95% CI − 1.50 to − 0.58; P < 0.01) WMD − 0.71 days; 95% confidence interval (CI), − 1.08 to − 0.34; P < 0.01, respectively) while compared to those with IVATS. There were no significant differences in postoperative complication rate, surgical duration, and the number of dissected lymph nodes. However, through the analysis of highly selected patients with lung cancer in early stage, the rate of postoperative complication in the NIVATS group was lower than that in the IVATS group [odds ratio (OR) 0.44; 95% CI 0.21–0.92; P = 0.03, I 2 = 0%]. Conclusions Although the comparable postoperative complication rate was observed for major thoracic surgery in two surgical procedures, the NIVATS method could significantly shorten the hospitalized stay and chest-tube placement time compared with IVATS. Therefore, for highly selected patients, NIVATS is regarded as a safe and technically feasible procedure for major thoracic surgery. The assessment of the safety and feasibility for patients undergoing NIVATS needs further multi-center prospective clinical trials. |
topic |
Thoracic surgery Non-intubated anesthesia Major lung resection Lobectomy Segmentectomy Spontaneous breathing |
url |
https://doi.org/10.1186/s12957-021-02181-x |
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