Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females
Objective: It has been reported that the mortality due to ischemic stroke is higher and the prognosis is worse in women compared with men. The aim of this study was to determine the etiologic subtypes, risk factors, and prognosis of acute ischemic stroke (AIS) in females. Materials and Methods: We...
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Galenos Yayinevi
2021-06-01
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Series: | Türk Nöroloji Dergisi |
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Online Access: | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-09086&look4= |
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Eda Aslanbaba Bahadır Mine Hayriye Sorgun Zerin Özaydın Aksun Tehran Allahverdiyev Onur Bulut Şeyda Erdoğan Fatma Tuğra Karaarslan Aygül Nadirova Büşra Ölmez Canay Önder Turgut Şahin Ömer Eray Yalap Zehra Yavuz Abdullah Yasir Yılmaz Mustafa Erdoğan Canan Togay Işıkay |
spellingShingle |
Eda Aslanbaba Bahadır Mine Hayriye Sorgun Zerin Özaydın Aksun Tehran Allahverdiyev Onur Bulut Şeyda Erdoğan Fatma Tuğra Karaarslan Aygül Nadirova Büşra Ölmez Canay Önder Turgut Şahin Ömer Eray Yalap Zehra Yavuz Abdullah Yasir Yılmaz Mustafa Erdoğan Canan Togay Işıkay Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females Türk Nöroloji Dergisi acute ischemic stroke female ischemic stroke etiology risk factors |
author_facet |
Eda Aslanbaba Bahadır Mine Hayriye Sorgun Zerin Özaydın Aksun Tehran Allahverdiyev Onur Bulut Şeyda Erdoğan Fatma Tuğra Karaarslan Aygül Nadirova Büşra Ölmez Canay Önder Turgut Şahin Ömer Eray Yalap Zehra Yavuz Abdullah Yasir Yılmaz Mustafa Erdoğan Canan Togay Işıkay |
author_sort |
Eda Aslanbaba Bahadır |
title |
Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females |
title_short |
Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females |
title_full |
Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females |
title_fullStr |
Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females |
title_full_unstemmed |
Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in Females |
title_sort |
etiologic subtypes, risk factors and early outcome of acute ischemic stroke in females |
publisher |
Galenos Yayinevi |
series |
Türk Nöroloji Dergisi |
issn |
1309-2545 |
publishDate |
2021-06-01 |
description |
Objective: It has been reported that the mortality due to ischemic stroke is higher and the prognosis is worse in women compared with men. The aim of this study was to determine the etiologic subtypes, risk factors, and prognosis of acute ischemic stroke (AIS) in females.
Materials and Methods: We reviewed the medical records of 957 patients who were admitted with AIS between January 2011 and May 2017. The patients’ records were analyzed and the demographic data, risk factors, National Institutes of Health Stroke Scale (NIHSS) scores at admission, and modified Rankin Scale (mRS) in the follow-up were recorded. We determined etiologic stroke subtypes using the Automated Causative Classification System.
Results: In the study, 432 (45.1%) female patients [mean age: 71.2±14.7 (range: 21-100) years] and 525 (54.9%) male patients [mean age: 67.2±12.9 (range: 25-103) years] were included. The women were older than the men (p<0.001). Atrial fibrillation (AF) and congestive heart failure were more common in females (p<0.001). Otherwise, coronary artery disease was more common in males (p<0.001). NIHSS score at admission and the number of patients with mRS scores over 2 in the follow-up after discharge were higher in female patients than in male patients (p<0.05). The most common ischemic stroke etiology in females was cardioembolism (48.4%), whereas it was in major large artery atherosclerosis in males (31.6%). On logistic regression analysis, AF and cardio-aortic embolism were significantly associated with female sex (p<0.05).
Conclusion: In our series, AIS was more severe and caused more disability in females compared with males. AF was more common as an underlying etiology of ischemic stroke in females. These results reveal the importance of AF screening and anticoagulant treatment prophylaxis in the older female population. |
topic |
acute ischemic stroke female ischemic stroke etiology risk factors |
url |
https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-09086&look4= |
work_keys_str_mv |
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doaj-4768602cc7674aeb8c3cde14bfb5d9df2021-10-04T10:34:40ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452021-06-0127218719110.4274/tnd.2021.09086Etiologic Subtypes, Risk Factors and Early Outcome of Acute Ischemic Stroke in FemalesEda Aslanbaba Bahadır0https://orcid.org/0000-0002-6542-9663Mine Hayriye Sorgun1https://orcid.org/0000-0003-2370-7319Zerin Özaydın Aksun2https://orcid.org/0000-0003-1154-4276Tehran Allahverdiyev3https://orcid.org/0000-0003-4456-1849Onur Bulut4https://orcid.org/0000-0003-4995-7025Şeyda Erdoğan5https://orcid.org/0000-0003-2759-9562Fatma Tuğra Karaarslan6https://orcid.org/0000-0001-7210-4923Aygül Nadirova7https://orcid.org/0000-0003-3298-5767Büşra Ölmez8https://orcid.org/0000-0001-9618-0496Canay Önder9https://orcid.org/0000-0002-6964-0896Turgut Şahin10https://orcid.org/0000-0002-5757-2590Ömer Eray Yalap11https://orcid.org/0000-0001-9900-0745Zehra Yavuz12https://orcid.org/0000-0002-3627-5212Abdullah Yasir Yılmaz13https://orcid.org/0000-0001-7143-164XMustafa Erdoğan14https://orcid.org/0000-0003-0109-2296Canan Togay Işıkay15https://orcid.org/0000-0001-6256-9487Ankara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Biostatistics, Ankara, TurkeyAnkara University Faculty of Medicine, Department of Neurology, Ankara, TurkeyObjective: It has been reported that the mortality due to ischemic stroke is higher and the prognosis is worse in women compared with men. The aim of this study was to determine the etiologic subtypes, risk factors, and prognosis of acute ischemic stroke (AIS) in females. Materials and Methods: We reviewed the medical records of 957 patients who were admitted with AIS between January 2011 and May 2017. The patients’ records were analyzed and the demographic data, risk factors, National Institutes of Health Stroke Scale (NIHSS) scores at admission, and modified Rankin Scale (mRS) in the follow-up were recorded. We determined etiologic stroke subtypes using the Automated Causative Classification System. Results: In the study, 432 (45.1%) female patients [mean age: 71.2±14.7 (range: 21-100) years] and 525 (54.9%) male patients [mean age: 67.2±12.9 (range: 25-103) years] were included. The women were older than the men (p<0.001). Atrial fibrillation (AF) and congestive heart failure were more common in females (p<0.001). Otherwise, coronary artery disease was more common in males (p<0.001). NIHSS score at admission and the number of patients with mRS scores over 2 in the follow-up after discharge were higher in female patients than in male patients (p<0.05). The most common ischemic stroke etiology in females was cardioembolism (48.4%), whereas it was in major large artery atherosclerosis in males (31.6%). On logistic regression analysis, AF and cardio-aortic embolism were significantly associated with female sex (p<0.05). Conclusion: In our series, AIS was more severe and caused more disability in females compared with males. AF was more common as an underlying etiology of ischemic stroke in females. These results reveal the importance of AF screening and anticoagulant treatment prophylaxis in the older female population.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-09086&look4=acute ischemic strokefemaleischemic stroke etiologyrisk factors |