The protective effects of omega-3 fatty acids on rat testicular tissue

Objectives: In this study, the protective effect of omega-3 fatty acids on testicular tissue was aimed to investigate at biochemical levels.Materials and methods: Totally, 16 adult male Wistar rats were divided into two groups. Rats in Group I were used as control and only saline was given by intrag...

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Main Authors: İsmail Zararsız, İlter Kuş, Mürsel Davarcı, Murat Abdulgani Kuş, Dilara Kaman, Mustafa Sarsılmaz
Format: Article
Language:English
Published: Dicle University Medical School 2011-12-01
Series:Dicle Medical Journal
Subjects:
rat
Online Access:http://www.dicle.edu.tr/fakulte/tip/dergi/yayin/384/02.pdf
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spelling doaj-47697a30d88349b3ba46165acb15f7312020-11-24T22:52:03ZengDicle University Medical SchoolDicle Medical Journal 1300-29451308-98892011-12-01384382386The protective effects of omega-3 fatty acids on rat testicular tissueİsmail Zararsızİlter KuşMürsel DavarcıMurat Abdulgani KuşDilara KamanMustafa SarsılmazObjectives: In this study, the protective effect of omega-3 fatty acids on testicular tissue was aimed to investigate at biochemical levels.Materials and methods: Totally, 16 adult male Wistar rats were divided into two groups. Rats in Group I were used as control and only saline was given by intragastric gavage. Rats in Group II, 400 mg/kg dose ω-3 fatty acids were given daily by intragastric gavage. At the end of the six-week experimental period, all rats were killed by decapitation. The testicular tissue specimens taken from animals, superoxide dismutase, glutathione peroxidase, malondialdehyde, enzyme activities were measured spectrophotometrically. In addition, blood testosterone levels were examined.Results: In our study, ω-3 fatty acids in rats were given a statistically significant increase in the levels of superoxide dismutase, and glutathione peroxidase a statistically significant decrease in malondialdehyde levels were determined when compared to control group. In addition, ω-3 fatty acids in rats given a statistically significant increase in blood testosterone levels were observed.Conclusion: We concluded that ω-3 fatty acid had favorable effects in rat testis tissue by preventing oxidative damage and increasing the level of testosterone.http://www.dicle.edu.tr/fakulte/tip/dergi/yayin/384/02.pdfω-3 fatty acidstesticletestosteronerat
collection DOAJ
language English
format Article
sources DOAJ
author İsmail Zararsız
İlter Kuş
Mürsel Davarcı
Murat Abdulgani Kuş
Dilara Kaman
Mustafa Sarsılmaz
spellingShingle İsmail Zararsız
İlter Kuş
Mürsel Davarcı
Murat Abdulgani Kuş
Dilara Kaman
Mustafa Sarsılmaz
The protective effects of omega-3 fatty acids on rat testicular tissue
Dicle Medical Journal
ω-3 fatty acids
testicle
testosterone
rat
author_facet İsmail Zararsız
İlter Kuş
Mürsel Davarcı
Murat Abdulgani Kuş
Dilara Kaman
Mustafa Sarsılmaz
author_sort İsmail Zararsız
title The protective effects of omega-3 fatty acids on rat testicular tissue
title_short The protective effects of omega-3 fatty acids on rat testicular tissue
title_full The protective effects of omega-3 fatty acids on rat testicular tissue
title_fullStr The protective effects of omega-3 fatty acids on rat testicular tissue
title_full_unstemmed The protective effects of omega-3 fatty acids on rat testicular tissue
title_sort protective effects of omega-3 fatty acids on rat testicular tissue
publisher Dicle University Medical School
series Dicle Medical Journal
issn 1300-2945
1308-9889
publishDate 2011-12-01
description Objectives: In this study, the protective effect of omega-3 fatty acids on testicular tissue was aimed to investigate at biochemical levels.Materials and methods: Totally, 16 adult male Wistar rats were divided into two groups. Rats in Group I were used as control and only saline was given by intragastric gavage. Rats in Group II, 400 mg/kg dose ω-3 fatty acids were given daily by intragastric gavage. At the end of the six-week experimental period, all rats were killed by decapitation. The testicular tissue specimens taken from animals, superoxide dismutase, glutathione peroxidase, malondialdehyde, enzyme activities were measured spectrophotometrically. In addition, blood testosterone levels were examined.Results: In our study, ω-3 fatty acids in rats were given a statistically significant increase in the levels of superoxide dismutase, and glutathione peroxidase a statistically significant decrease in malondialdehyde levels were determined when compared to control group. In addition, ω-3 fatty acids in rats given a statistically significant increase in blood testosterone levels were observed.Conclusion: We concluded that ω-3 fatty acid had favorable effects in rat testis tissue by preventing oxidative damage and increasing the level of testosterone.
topic ω-3 fatty acids
testicle
testosterone
rat
url http://www.dicle.edu.tr/fakulte/tip/dergi/yayin/384/02.pdf
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