Pediatric adrenocortical tumors: what they can tell us on adrenal development and comparison with adult adrenal tumors

Adrenocortical tumors (ACT) in children are very rare and are most frequently diagnosed in the context of the Li-Fraumeni syndrome, a multiple cancer syndrome linked to germline mutations of the tumor suppressor gene TP53 with loss of heterozygosity in the tumors. A peak of children ACT incidence is...

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Bibliographic Details
Main Authors: Enzo eLalli, Bonald C. Figueiredo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00023/full

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