Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9
It is well known that myogenic regulatory factors encoded by the Myod1 family of genes have pivotal roles in myogenesis, with partially overlapping functions, as demonstrated for the mouse embryo. Myogenin-mutant mice, however, exhibit severe myogenic defects without compensation by other myogenic f...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2017-01-01
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Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2017/9210494 |