Effects of Phyllanthus niruri on the severity of the common cold in children
Background Common cold is a selflimited disease, however it poses a significant burden on productivity and community health. Unfortunately, there has been no standard medication for childhood common cold, whereas some herbs \\lith immune modulating properties, such as Phyllanthus niruri extract (P...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Indonesian Pediatric Society Publishing House
2012-12-01
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Series: | Paediatrica Indonesiana |
Subjects: | |
Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/499 |
Summary: | Background Common cold is a selflimited disease, however
it poses a significant burden on productivity and community
health. Unfortunately, there has been no standard medication
for childhood common cold, whereas some herbs \\lith immune
modulating properties, such as Phyllanthus niruri extract (PNE),
might be beneficial but has not been thoroughly studied.
Objective To evaluate the effect of PNE administration on the
severity of common cold symptoms in children.
Methods We performed a randomized, doubleblind, controlled
trial in children aged 26 years who were diagnosed Mth a common
cold at primary health care centers in Sewon and Jetis in Bantul,
as well as in Gondomanan and Gedongtengen in Yogyakarta.
Subjects were collected by consecutive sampling and parents
were interviewed. We assessed illness severity by Hemila scoring
for the common cold.
Results A total of 100 subjects were included Mth 50 subjects in
each intervention group. After treatment, there was no significant
difference in common cold severity between the PNE and the
control groups for all symptom score components, including cough
(0.87 vs 0.71, P0.36), nasal symptom (0.90 vs 1.10, P0.54),
coryza ( 0.44 vs 1.10, P=0.54), and systemic symptom (0.10 vs
0.10, P0.94).
Conclusion Administration of PNE for 6 days did not provide a
significant benefit in reducing the severity of the common cold
compared to placebo in children aged 2 - 6 years. [Paediatr
Indanes.2012;52:346-51]. |
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ISSN: | 0030-9311 2338-476X |