An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning

Deep learning for digital pathology is hindered by the extremely high spatial resolution of whole slide images (WSIs), which requires researchers to adopt patch-based methods and laborious free-hand contouring. Here, the authors develop a whole-slide training method to classify types of lung cancers...

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Main Authors: Chi-Long Chen, Chi-Chung Chen, Wei-Hsiang Yu, Szu-Hua Chen, Yu-Chan Chang, Tai-I Hsu, Michael Hsiao, Chao-Yuan Yeh, Cheng-Yu Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21467-y
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spelling doaj-47ff16da572b44e18dc48650a6b00d472021-02-21T12:11:56ZengNature Publishing GroupNature Communications2041-17232021-02-0112111310.1038/s41467-021-21467-yAn annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learningChi-Long Chen0Chi-Chung Chen1Wei-Hsiang Yu2Szu-Hua Chen3Yu-Chan Chang4Tai-I Hsu5Michael Hsiao6Chao-Yuan Yeh7Cheng-Yu Chen8Department of Pathology, School of Medicine, College of Medicine, Taipei Medical UniversityaetherAI Co., Ltd.aetherAI Co., Ltd.aetherAI Co., Ltd.Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming UniversityGenomics Research Center, Academia SinicaGenomics Research Center, Academia SinicaaetherAI Co., Ltd.Department of Radiology, School of Medicine, College of Medicine, Taipei Medical UniversityDeep learning for digital pathology is hindered by the extremely high spatial resolution of whole slide images (WSIs), which requires researchers to adopt patch-based methods and laborious free-hand contouring. Here, the authors develop a whole-slide training method to classify types of lung cancers using slide-level diagnoses with deep learning.https://doi.org/10.1038/s41467-021-21467-y
collection DOAJ
language English
format Article
sources DOAJ
author Chi-Long Chen
Chi-Chung Chen
Wei-Hsiang Yu
Szu-Hua Chen
Yu-Chan Chang
Tai-I Hsu
Michael Hsiao
Chao-Yuan Yeh
Cheng-Yu Chen
spellingShingle Chi-Long Chen
Chi-Chung Chen
Wei-Hsiang Yu
Szu-Hua Chen
Yu-Chan Chang
Tai-I Hsu
Michael Hsiao
Chao-Yuan Yeh
Cheng-Yu Chen
An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
Nature Communications
author_facet Chi-Long Chen
Chi-Chung Chen
Wei-Hsiang Yu
Szu-Hua Chen
Yu-Chan Chang
Tai-I Hsu
Michael Hsiao
Chao-Yuan Yeh
Cheng-Yu Chen
author_sort Chi-Long Chen
title An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
title_short An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
title_full An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
title_fullStr An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
title_full_unstemmed An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
title_sort annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-02-01
description Deep learning for digital pathology is hindered by the extremely high spatial resolution of whole slide images (WSIs), which requires researchers to adopt patch-based methods and laborious free-hand contouring. Here, the authors develop a whole-slide training method to classify types of lung cancers using slide-level diagnoses with deep learning.
url https://doi.org/10.1038/s41467-021-21467-y
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