PATHOGENICITY FACTORS OF CORYNEBACTERIUM NON DIPHTHERIAE

• Main Authors: G. G. Kharseeva, N. A. Voronina
• Format: Article
• Language: Russian
• Published: Central Research Institute for Epidemiology 2016-06-01
• Series: Журнал микробиологии, эпидемиологии и иммунобиологии
• Subjects: corynebacterium non diphtheriae; pld-экзотоксин; corynebacterium pseudotuberculosis; pld-exotoxin; pathogenicity enzymes; pili (fimbriae)
• Online Access: https://microbiol.elpub.ru/jour/article/view/56

Pathogenicity factors of Corynebacterium non diphtheriae - pili, microcapsule, cell wall, pathogenicity enzymes, toxins, that determine the ability of microorganisms to consequentially interact with epithelium of entry gates of the organism, replicate in vivo, overcome cell and humoral mechanisms of protection, are examined in the review. Particular attention in the paper is given to species of non-diphtheria corynebacteria, that are pathogenic for human and able to produce toxins - Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Mechanisms of expression regulation of PLD-exotoxins, its interaction with immune system cells are described.