Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants
The ubiquitous glyoxalase enzymatic pathway is involved in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis. The glyoxalase system has been more extensively studied in animals versus plants. Plant glyoxalases have been primarily associated with stress responses and their...
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doaj-480a17179758431a835a90076c1cdad92020-11-25T02:01:41ZengMDPI AGInternational Journal of Molecular Sciences1422-00672017-04-0118489810.3390/ijms18040898ijms18040898Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in PlantsSubramanian Sankaranarayanan0Muhammad Jamshed1Abhinandan Kumar2Logan Skori3Sabine Scandola4Tina Wang5David Spiegel6Marcus A. Samuel7Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, CanadaDepartment of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, CanadaDepartment of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, CanadaDepartment of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, CanadaDepartment of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, CanadaDepartment of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06511, USADepartment of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06511, USADepartment of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, CanadaThe ubiquitous glyoxalase enzymatic pathway is involved in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis. The glyoxalase system has been more extensively studied in animals versus plants. Plant glyoxalases have been primarily associated with stress responses and their overexpression is known to impart tolerance to various abiotic stresses. In plants, glyoxalases exist as multigene families, and new roles for glyoxalases in various developmental and signaling pathways have started to emerge. Glyoxalase-based MG detoxification has now been shown to be important for pollination responses. During self-incompatibility response in Brassicaceae, MG is required to target compatibility factors for proteasomal degradation, while accumulation of glyoxalase leads to MG detoxification and efficient pollination. In this review, we discuss the importance of glyoxalase systems and their emerging biological roles in plants.http://www.mdpi.com/1422-0067/18/4/898glyoxalasemethylglyoxalplantsdevelopmentstress response |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Subramanian Sankaranarayanan Muhammad Jamshed Abhinandan Kumar Logan Skori Sabine Scandola Tina Wang David Spiegel Marcus A. Samuel |
spellingShingle |
Subramanian Sankaranarayanan Muhammad Jamshed Abhinandan Kumar Logan Skori Sabine Scandola Tina Wang David Spiegel Marcus A. Samuel Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants International Journal of Molecular Sciences glyoxalase methylglyoxal plants development stress response |
author_facet |
Subramanian Sankaranarayanan Muhammad Jamshed Abhinandan Kumar Logan Skori Sabine Scandola Tina Wang David Spiegel Marcus A. Samuel |
author_sort |
Subramanian Sankaranarayanan |
title |
Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants |
title_short |
Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants |
title_full |
Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants |
title_fullStr |
Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants |
title_full_unstemmed |
Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants |
title_sort |
glyoxalase goes green: the expanding roles of glyoxalase in plants |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2017-04-01 |
description |
The ubiquitous glyoxalase enzymatic pathway is involved in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis. The glyoxalase system has been more extensively studied in animals versus plants. Plant glyoxalases have been primarily associated with stress responses and their overexpression is known to impart tolerance to various abiotic stresses. In plants, glyoxalases exist as multigene families, and new roles for glyoxalases in various developmental and signaling pathways have started to emerge. Glyoxalase-based MG detoxification has now been shown to be important for pollination responses. During self-incompatibility response in Brassicaceae, MG is required to target compatibility factors for proteasomal degradation, while accumulation of glyoxalase leads to MG detoxification and efficient pollination. In this review, we discuss the importance of glyoxalase systems and their emerging biological roles in plants. |
topic |
glyoxalase methylglyoxal plants development stress response |
url |
http://www.mdpi.com/1422-0067/18/4/898 |
work_keys_str_mv |
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