Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients
Toxoplasmosis is a wide distributed opportunistic infection caused by Toxoplasma gondii. This was a cross-sectional study of T. gondii antibody titer, which was conducted from June 2003 to August 2004 on renal transplant recipients in Iran. A total of 551 serum samples were obtained from randomly se...
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Tehran University of Medical Sciences
2006-12-01
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doaj-480c3ddeaaef403e8474e743dbcd65ea2021-04-02T11:23:31ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2006-12-0111Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients M Nateghi Rostami0 E Eskandari1 Z Garoosi2 N Mohajeri3 M Rezaian4 H Keshavarz5 Toxoplasmosis is a wide distributed opportunistic infection caused by Toxoplasma gondii. This was a cross-sectional study of T. gondii antibody titer, which was conducted from June 2003 to August 2004 on renal transplant recipients in Iran. A total of 551 serum samples were obtained from randomly selected population referred from different areas all over the country to Shafa Central Clinic in Tehran. Patient’s information was recorded in a questionnaire before sampling. Two samples of finger-prick blood were collected from each person and antibody titer against Toxoplasma was assessed by Indirect Fluorescence Antibody (IFA) technique on serum samples. Totally 39 cases (7.1%) of samples were positive for antibody by the titer of 1: 20 and higher. On investigation of risk factors, no significant difference was found between consumption of under-cooked meat, close contact with animals, and the source of drinking water and seropositivity rate of toxoplasmosis. The relatively low seroprevalence rate of Toxoplasma infection shows the successful approaches to awareness of transplant recipients about the potential risks of acquisition of infectious diseases due to regular administration of suppressive drugs. However, the regular surveillance through serological screening of Toxoplasma antibody in kidney transplant recipients is advisable.https://ijpa.tums.ac.ir/index.php/ijpa/article/view/5Renal transplant recipients |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
M Nateghi Rostami E Eskandari Z Garoosi N Mohajeri M Rezaian H Keshavarz |
spellingShingle |
M Nateghi Rostami E Eskandari Z Garoosi N Mohajeri M Rezaian H Keshavarz Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients Iranian Journal of Parasitology Renal transplant recipients |
author_facet |
M Nateghi Rostami E Eskandari Z Garoosi N Mohajeri M Rezaian H Keshavarz |
author_sort |
M Nateghi Rostami |
title |
Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients |
title_short |
Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients |
title_full |
Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients |
title_fullStr |
Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients |
title_full_unstemmed |
Serological Study of Toxoplasma gondii Infection Using IFA Method in Renal Transplant Recipients |
title_sort |
serological study of toxoplasma gondii infection using ifa method in renal transplant recipients |
publisher |
Tehran University of Medical Sciences |
series |
Iranian Journal of Parasitology |
issn |
1735-7020 2008-238X |
publishDate |
2006-12-01 |
description |
Toxoplasmosis is a wide distributed opportunistic infection caused by Toxoplasma gondii. This was a cross-sectional study of T. gondii antibody titer, which was conducted from June 2003 to August 2004 on renal transplant recipients in Iran. A total of 551 serum samples were obtained from randomly selected population referred from different areas all over the country to Shafa Central Clinic in Tehran. Patient’s information was recorded in a questionnaire before sampling. Two samples of finger-prick blood were collected from each person and antibody titer against Toxoplasma was assessed by Indirect Fluorescence Antibody (IFA) technique on serum samples. Totally 39 cases (7.1%) of samples were positive for antibody by the titer of 1: 20 and higher. On investigation of risk factors, no significant difference was found between consumption of under-cooked meat, close contact with animals, and the source of drinking water and seropositivity rate of toxoplasmosis. The relatively low seroprevalence rate of Toxoplasma infection shows the successful approaches to awareness of transplant recipients about the potential risks of acquisition of infectious diseases due to regular administration of suppressive drugs. However, the regular surveillance through serological screening of Toxoplasma antibody in kidney transplant recipients is advisable. |
topic |
Renal transplant recipients |
url |
https://ijpa.tums.ac.ir/index.php/ijpa/article/view/5 |
work_keys_str_mv |
AT mnateghirostami serologicalstudyoftoxoplasmagondiiinfectionusingifamethodinrenaltransplantrecipients AT eeskandari serologicalstudyoftoxoplasmagondiiinfectionusingifamethodinrenaltransplantrecipients AT zgaroosi serologicalstudyoftoxoplasmagondiiinfectionusingifamethodinrenaltransplantrecipients AT nmohajeri serologicalstudyoftoxoplasmagondiiinfectionusingifamethodinrenaltransplantrecipients AT mrezaian serologicalstudyoftoxoplasmagondiiinfectionusingifamethodinrenaltransplantrecipients AT hkeshavarz serologicalstudyoftoxoplasmagondiiinfectionusingifamethodinrenaltransplantrecipients |
_version_ |
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