Removal of endotoxins from bacteriophage preparations by extraction with organic solvents.
Lipopolysaccharide (LPS, endotoxin, pyrogen) constitutes a very troubling contaminant of crude phage lysates produced in Gram-negative bacteria. Toxicity of LPS depends on the strong innate immunity response including the cytokines. Therefore, its removal is important for bacteriophage applications....
Main Authors: | Bożena Szermer-Olearnik, Janusz Boratyński |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4374689?pdf=render |
Similar Items
-
New Insights on the Feature and Function of Tail Tubular Protein B and Tail Fiber Protein of the Lytic Bacteriophage φYeO3-12 Specific for <i>Yersinia enterocolitica</i> Serotype O:3
by: Anna Pyra, et al.
Published: (2020-09-01) -
Aggregation/dispersion transitions of T4 phage triggered by environmental ion availability
by: Bożena Szermer-Olearnik, et al.
Published: (2017-04-01) -
The Removal of Endo- and Enterotoxins From Bacteriophage Preparations
by: Ville Hietala, et al.
Published: (2019-07-01) -
Comparison of microbiological and physicochemical methods for enumeration of microorganisms
by: Bożena Szermer-Olearnik, et al.
Published: (2014-01-01) -
Membrane adsorber for endotoxin removal
by: Karina Moita de Almeida, et al.