Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis
Objectives: The aim of this study was to assess the characteristics of periprosthetic joint infection (PJI) due to Staphylococcus lugdunensis and to compare these to the characteristics of PJI due to Staphylococcus aureus and Staphylococcus epidermidis. Methods: A retrospective multicentre study inc...
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doaj-484a0477b750423baed8eeecf6297cde2020-11-25T01:00:55ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112016-10-0151C566110.1016/j.ijid.2016.08.007Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidisJ. Lourtet-Hascoët0A. Bicart-See1M.P. Félicé2G. Giordano3E. Bonnet4Microbiological Laboratory, Hôpital J. Ducuing, 15 rue Varsovie, 31300 Toulouse, FranceInfectious Diseases Mobile Unit, J. Ducuing Hospital, Toulouse, FranceMicrobiological Laboratory, Hôpital J. Ducuing, 15 rue Varsovie, 31300 Toulouse, FranceTraumatology and Orthopaedic Surgery Department, J. Ducuing Hospital, Toulouse, FranceInfectious Diseases Mobile Unit, J. Ducuing Hospital, Toulouse, FranceObjectives: The aim of this study was to assess the characteristics of periprosthetic joint infection (PJI) due to Staphylococcus lugdunensis and to compare these to the characteristics of PJI due to Staphylococcus aureus and Staphylococcus epidermidis. Methods: A retrospective multicentre study including all consecutive cases of S. lugdunensis PJI (2000–2014) was performed. Eighty-eight cases of staphylococcal PJI were recorded: 28 due to S. lugdunensis, 30 to S. aureus, and 30 to S. epidermidis, as identified by Vitek 2 or API Staph (bioMérieux). Results: Clinical symptoms were more often reported in the S. lugdunensis group, and the median delay between surgery and infection was shorter for the S. lugdunensis group than for the S. aureus and S. epidermidis groups. Regarding antibiotic susceptibility, the S. lugdunensis strains were susceptible to antibiotics and 61% of the patients could be treated with levofloxacin + rifampicin. The outcome of the PJI was favourable for 89% of patients with S. lugdunensis, 83% with S. aureus, and 97% with S. epidermidis. Conclusion: S. lugdunensis is an emerging pathogen with a pathogenicity quite similar to that of S. aureus. This coagulase-negative Staphylococcus must be identified precisely in PJI, in order to select the appropriate surgical treatment and antibiotics .http://www.sciencedirect.com/science/article/pii/S1201971216311328Staphylococcus lugdunensisPeriprosthetic joint infectionStaphylococcus aureus |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
J. Lourtet-Hascoët A. Bicart-See M.P. Félicé G. Giordano E. Bonnet |
spellingShingle |
J. Lourtet-Hascoët A. Bicart-See M.P. Félicé G. Giordano E. Bonnet Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis International Journal of Infectious Diseases Staphylococcus lugdunensis Periprosthetic joint infection Staphylococcus aureus |
author_facet |
J. Lourtet-Hascoët A. Bicart-See M.P. Félicé G. Giordano E. Bonnet |
author_sort |
J. Lourtet-Hascoët |
title |
Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis |
title_short |
Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis |
title_full |
Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis |
title_fullStr |
Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis |
title_full_unstemmed |
Staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to Staphylococcus aureus and Staphylococcus epidermidis |
title_sort |
staphylococcus lugdunensis, a serious pathogen in periprosthetic joint infections: comparison to staphylococcus aureus and staphylococcus epidermidis |
publisher |
Elsevier |
series |
International Journal of Infectious Diseases |
issn |
1201-9712 1878-3511 |
publishDate |
2016-10-01 |
description |
Objectives: The aim of this study was to assess the characteristics of periprosthetic joint infection (PJI) due to Staphylococcus lugdunensis and to compare these to the characteristics of PJI due to Staphylococcus aureus and Staphylococcus epidermidis.
Methods: A retrospective multicentre study including all consecutive cases of S. lugdunensis PJI (2000–2014) was performed. Eighty-eight cases of staphylococcal PJI were recorded: 28 due to S. lugdunensis, 30 to S. aureus, and 30 to S. epidermidis, as identified by Vitek 2 or API Staph (bioMérieux).
Results: Clinical symptoms were more often reported in the S. lugdunensis group, and the median delay between surgery and infection was shorter for the S. lugdunensis group than for the S. aureus and S. epidermidis groups. Regarding antibiotic susceptibility, the S. lugdunensis strains were susceptible to antibiotics and 61% of the patients could be treated with levofloxacin + rifampicin. The outcome of the PJI was favourable for 89% of patients with S. lugdunensis, 83% with S. aureus, and 97% with S. epidermidis.
Conclusion: S. lugdunensis is an emerging pathogen with a pathogenicity quite similar to that of S. aureus. This coagulase-negative Staphylococcus must be identified precisely in PJI, in order to select the appropriate surgical treatment and antibiotics . |
topic |
Staphylococcus lugdunensis Periprosthetic joint infection Staphylococcus aureus |
url |
http://www.sciencedirect.com/science/article/pii/S1201971216311328 |
work_keys_str_mv |
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