Drug-induced hypersomnia
Daytime somnolence may be a symptom of different somatic, neurological and psychiatric diseases and develop due to abuse and/or discontinuation of various medications. Drug- induced hypersomnia (DIH) is defined as hypersomnolence caused by the intake of multiple drugs. DIH is one of the most freq...
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doaj-484a93dcb0244605b0a2f79727300de72021-07-29T08:58:42ZrusIMA-PRESS LLCNevrologiâ, Nejropsihiatriâ, Psihosomatika2074-27112310-13422021-04-0113211712210.14412/2074-2711-2021-2-117-1221121Drug-induced hypersomniaT. M. Ostroumova0O. D. Ostroumova1A. V. Filippova2T. F. Guseva3I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian FederationRussian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian FederationA.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of RussiaDaytime somnolence may be a symptom of different somatic, neurological and psychiatric diseases and develop due to abuse and/or discontinuation of various medications. Drug- induced hypersomnia (DIH) is defined as hypersomnolence caused by the intake of multiple drugs. DIH is one of the most frequently reported effects and/or side effects of drugs. DIH prevalence varies widely and can be as high as 75% in patients receiving specific medications. DIH risk factors include elderly and senile age, impaired drug metabolism, serum drug concentration, method and frequency of drug administration, single and daily doses of drugs, etc., as in many other drug- induced diseases and syndromes. DIH can occur both due to sedative agents administration and withdrawal of psychostimulants and other activating psychotropic medications. Most often, the development of DIH is associated with the use of levodopa-carbidopa, antipsychotics, antidepressants. The pathogenesis of DIH is complex and multifactorial and is associated with the mechanism of action of individual drugs and the presence of concomitant diseases. The article discusses the risk assessment of DIH development due to various medications, diagnosis and management tactics of patients with DIH.https://nnp.ima-press.net/nnp/article/view/1550hypersomniadrug-induced hypersomniamedicationadverse drug reactionside effects |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
T. M. Ostroumova O. D. Ostroumova A. V. Filippova T. F. Guseva |
spellingShingle |
T. M. Ostroumova O. D. Ostroumova A. V. Filippova T. F. Guseva Drug-induced hypersomnia Nevrologiâ, Nejropsihiatriâ, Psihosomatika hypersomnia drug-induced hypersomnia medication adverse drug reaction side effects |
author_facet |
T. M. Ostroumova O. D. Ostroumova A. V. Filippova T. F. Guseva |
author_sort |
T. M. Ostroumova |
title |
Drug-induced hypersomnia |
title_short |
Drug-induced hypersomnia |
title_full |
Drug-induced hypersomnia |
title_fullStr |
Drug-induced hypersomnia |
title_full_unstemmed |
Drug-induced hypersomnia |
title_sort |
drug-induced hypersomnia |
publisher |
IMA-PRESS LLC |
series |
Nevrologiâ, Nejropsihiatriâ, Psihosomatika |
issn |
2074-2711 2310-1342 |
publishDate |
2021-04-01 |
description |
Daytime somnolence may be a symptom of different somatic, neurological and psychiatric diseases and develop due to abuse and/or discontinuation of various medications. Drug- induced hypersomnia (DIH) is defined as hypersomnolence caused by the intake of multiple drugs. DIH is one of the most frequently reported effects and/or side effects of drugs. DIH prevalence varies widely and can be as high as 75% in patients receiving specific medications. DIH risk factors include elderly and senile age, impaired drug metabolism, serum drug concentration, method and frequency of drug administration, single and daily doses of drugs, etc., as in many other drug- induced diseases and syndromes. DIH can occur both due to sedative agents administration and withdrawal of psychostimulants and other activating psychotropic medications. Most often, the development of DIH is associated with the use of levodopa-carbidopa, antipsychotics, antidepressants. The pathogenesis of DIH is complex and multifactorial and is associated with the mechanism of action of individual drugs and the presence of concomitant diseases. The article discusses the risk assessment of DIH development due to various medications, diagnosis and management tactics of patients with DIH. |
topic |
hypersomnia drug-induced hypersomnia medication adverse drug reaction side effects |
url |
https://nnp.ima-press.net/nnp/article/view/1550 |
work_keys_str_mv |
AT tmostroumova druginducedhypersomnia AT odostroumova druginducedhypersomnia AT avfilippova druginducedhypersomnia AT tfguseva druginducedhypersomnia |
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1721250493830791168 |