Analytical Evaluation of the Ideal Strategy for High-Throughput Flow Injection Analysis by Tandem Mass Spectrometry in Routine Newborn Screening

Analytical Evaluation of the Ideal Strategy for High-Throughput Flow Injection Analysis by Tandem Mass Spectrometry in Routine Newborn Screening

The introduction of tandem mass spectrometry (MS/MS) to clinical laboratories and the advent of expanded newborn screening (NBS) were crucial changes to public health programs worldwide. Speed, robustness, accuracy, selectivity, and specificity of analysis are all requirements of expanded NBS and ar...

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Bibliographic Details
Main Authors: Ilaria Cicalini, Silvia Valentinuzzi, Damiana Pieragostino, Ada Consalvo, Mirco Zucchelli, Simone Donzelli, Davide Ambrogi, Heather A. Brown, Lisa J. Calton, Liborio Stuppia, Vincenzo De Laurenzi, Piero Del Boccio, Claudia Rossi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Metabolites
Subjects:
metabolomics
newborn screening
metabolites
high-throughput omics technologies
mass spectrometry
inborn errors of metabolism
Online Access:https://www.mdpi.com/2218-1989/11/8/473

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