The effects of increased dose of hepatitis B vaccine on mother-to-child transmission and immune response for infants born to mothers with chronic hepatitis B infection: a prospective, multicenter, large-sample cohort study
Abstract Background Appropriate passive-active immunoprophylaxis effectively reduces mother-to-child transmission (MTCT) of hepatitis B virus (HBV), but the immunoprophylaxis failure was still more than 5% under the current strategy. The study objective was to investigate the effects of high dose of...
Main Authors: | Xiaohui Zhang, Huaibin Zou, Yu Chen, Hua Zhang, Ruihua Tian, Jun Meng, Yunxia Zhu, Huimin Guo, Erhei Dai, Baoshen Zhu, Zhongsheng Liu, Yanxia Jin, Yujie Li, Liping Feng, Hui Zhuang, Calvin Q. Pan, Jie Li, Zhongping Duan |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | BMC Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12916-021-02025-1 |
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