Gene networks that compensate for crosstalk with crosstalk

Crosstalk between genetic circuits is a major challenge for engineering sophisticated networks. Here the authors design networks that compensate for crosstalk by integrating, not insulating, pathways.

Bibliographic Details
Main Authors: Isaak E. Müller, Jacob R. Rubens, Tomi Jun, Daniel Graham, Ramnik Xavier, Timothy K. Lu
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12021-y
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spelling doaj-48582d3c905240f89f9e28753fe44f6b2021-05-11T11:33:03ZengNature Publishing GroupNature Communications2041-17232019-09-011011810.1038/s41467-019-12021-yGene networks that compensate for crosstalk with crosstalkIsaak E. Müller0Jacob R. Rubens1Tomi Jun2Daniel Graham3Ramnik Xavier4Timothy K. Lu5Synthetic Biology Group, MIT Synthetic Biology Center, Research Laboratory of Electronics, Department of Electrical Engineering & Computer Science, Massachusetts Institute of TechnologySynthetic Biology Group, MIT Synthetic Biology Center, Research Laboratory of Electronics, Department of Electrical Engineering & Computer Science, Massachusetts Institute of TechnologySynthetic Biology Group, MIT Synthetic Biology Center, Research Laboratory of Electronics, Department of Electrical Engineering & Computer Science, Massachusetts Institute of TechnologyProgram in Medical and Population Genetics, Broad InstituteProgram in Medical and Population Genetics, Broad InstituteSynthetic Biology Group, MIT Synthetic Biology Center, Research Laboratory of Electronics, Department of Electrical Engineering & Computer Science, Massachusetts Institute of TechnologyCrosstalk between genetic circuits is a major challenge for engineering sophisticated networks. Here the authors design networks that compensate for crosstalk by integrating, not insulating, pathways.https://doi.org/10.1038/s41467-019-12021-y
collection DOAJ
language English
format Article
sources DOAJ
author Isaak E. Müller
Jacob R. Rubens
Tomi Jun
Daniel Graham
Ramnik Xavier
Timothy K. Lu
spellingShingle Isaak E. Müller
Jacob R. Rubens
Tomi Jun
Daniel Graham
Ramnik Xavier
Timothy K. Lu
Gene networks that compensate for crosstalk with crosstalk
Nature Communications
author_facet Isaak E. Müller
Jacob R. Rubens
Tomi Jun
Daniel Graham
Ramnik Xavier
Timothy K. Lu
author_sort Isaak E. Müller
title Gene networks that compensate for crosstalk with crosstalk
title_short Gene networks that compensate for crosstalk with crosstalk
title_full Gene networks that compensate for crosstalk with crosstalk
title_fullStr Gene networks that compensate for crosstalk with crosstalk
title_full_unstemmed Gene networks that compensate for crosstalk with crosstalk
title_sort gene networks that compensate for crosstalk with crosstalk
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-09-01
description Crosstalk between genetic circuits is a major challenge for engineering sophisticated networks. Here the authors design networks that compensate for crosstalk by integrating, not insulating, pathways.
url https://doi.org/10.1038/s41467-019-12021-y
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