Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review

Background: Dyslipidemia is considered as an important modifiable risk factor for cardiovascular disease (CVD). The link between childhood dyslipidemia and occurrence of atherosclerosis and its sequels in adulthood are well-documented. This study aimed to systematically review the prevalence of dysl...

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Main Authors: Silva Hovsepian, Roya Kelishadi, Shirin Djalalinia, Farshad Farzadfar, Shohreh Naderimagham, Mostafa Qorbani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=5;spage=503;epage=521;aulast=Hovsepian
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spelling doaj-48686c3bc1104455b89b131f1e302cd52020-11-24T23:59:46ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362015-01-0120550352110.4103/1735-1995.163979Prevalence of dyslipidemia in Iranian children and adolescents: A systematic reviewSilva HovsepianRoya KelishadiShirin DjalaliniaFarshad FarzadfarShohreh NaderimaghamMostafa QorbaniBackground: Dyslipidemia is considered as an important modifiable risk factor for cardiovascular disease (CVD). The link between childhood dyslipidemia and occurrence of atherosclerosis and its sequels in adulthood are well-documented. This study aimed to systematically review the prevalence of dyslipidemia among Iranian children and adolescents. Materials and Methods: An electronic search was conducted on studies published from January 1990 to January 2014. The main international electronic data sources were PubMed and the NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS. For Persian databases, we used domestic databases with systematic search capability including IranMedex, Irandoc, and Scientific Information Database (SID). We included all available population-based studies and national surveys conducted in the pediatric age group (aged <21 years). Results: In this review, 1772 articles were identified (PubMed: 1464; Scopus: 11; ISI: 58; SID: 90; IranMedex: 149; Irandoc: 57). During three refine steps and after removing of duplicates, 182 articles related to the study domain were selected. After quality assessment, 46 studies were selected for text appraisal, of which 26 qualified articles were evaluated at the final step. The prevalence range of hypercholesterolemia, hypertriglyceridemia, elevated low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol (HDL-C) were 3-48%, 3-50%, 5-20% and 5-88%, respectively. Low HDL-C and hypertriglyceridemia were the most prevalent lipid disorders in this group of population. Conclusion: Dyslipidemia is a common health problem among Iranian children and adolescents. Few data were available in preschool children. This finding provides useful information for health policy makers to implement action-oriented interventions for prevention and early control of this important CVD risk factor.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=5;spage=503;epage=521;aulast=HovsepianDyslipidemiaIranlipid profilepediatricsprevalencesystematic review
collection DOAJ
language English
format Article
sources DOAJ
author Silva Hovsepian
Roya Kelishadi
Shirin Djalalinia
Farshad Farzadfar
Shohreh Naderimagham
Mostafa Qorbani
spellingShingle Silva Hovsepian
Roya Kelishadi
Shirin Djalalinia
Farshad Farzadfar
Shohreh Naderimagham
Mostafa Qorbani
Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
Journal of Research in Medical Sciences
Dyslipidemia
Iran
lipid profile
pediatrics
prevalence
systematic review
author_facet Silva Hovsepian
Roya Kelishadi
Shirin Djalalinia
Farshad Farzadfar
Shohreh Naderimagham
Mostafa Qorbani
author_sort Silva Hovsepian
title Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
title_short Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
title_full Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
title_fullStr Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
title_full_unstemmed Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
title_sort prevalence of dyslipidemia in iranian children and adolescents: a systematic review
publisher Wolters Kluwer Medknow Publications
series Journal of Research in Medical Sciences
issn 1735-1995
1735-7136
publishDate 2015-01-01
description Background: Dyslipidemia is considered as an important modifiable risk factor for cardiovascular disease (CVD). The link between childhood dyslipidemia and occurrence of atherosclerosis and its sequels in adulthood are well-documented. This study aimed to systematically review the prevalence of dyslipidemia among Iranian children and adolescents. Materials and Methods: An electronic search was conducted on studies published from January 1990 to January 2014. The main international electronic data sources were PubMed and the NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS. For Persian databases, we used domestic databases with systematic search capability including IranMedex, Irandoc, and Scientific Information Database (SID). We included all available population-based studies and national surveys conducted in the pediatric age group (aged <21 years). Results: In this review, 1772 articles were identified (PubMed: 1464; Scopus: 11; ISI: 58; SID: 90; IranMedex: 149; Irandoc: 57). During three refine steps and after removing of duplicates, 182 articles related to the study domain were selected. After quality assessment, 46 studies were selected for text appraisal, of which 26 qualified articles were evaluated at the final step. The prevalence range of hypercholesterolemia, hypertriglyceridemia, elevated low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol (HDL-C) were 3-48%, 3-50%, 5-20% and 5-88%, respectively. Low HDL-C and hypertriglyceridemia were the most prevalent lipid disorders in this group of population. Conclusion: Dyslipidemia is a common health problem among Iranian children and adolescents. Few data were available in preschool children. This finding provides useful information for health policy makers to implement action-oriented interventions for prevention and early control of this important CVD risk factor.
topic Dyslipidemia
Iran
lipid profile
pediatrics
prevalence
systematic review
url http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=5;spage=503;epage=521;aulast=Hovsepian
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