Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review
Background: Dyslipidemia is considered as an important modifiable risk factor for cardiovascular disease (CVD). The link between childhood dyslipidemia and occurrence of atherosclerosis and its sequels in adulthood are well-documented. This study aimed to systematically review the prevalence of dysl...
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Wolters Kluwer Medknow Publications
2015-01-01
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doaj-48686c3bc1104455b89b131f1e302cd52020-11-24T23:59:46ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362015-01-0120550352110.4103/1735-1995.163979Prevalence of dyslipidemia in Iranian children and adolescents: A systematic reviewSilva HovsepianRoya KelishadiShirin DjalaliniaFarshad FarzadfarShohreh NaderimaghamMostafa QorbaniBackground: Dyslipidemia is considered as an important modifiable risk factor for cardiovascular disease (CVD). The link between childhood dyslipidemia and occurrence of atherosclerosis and its sequels in adulthood are well-documented. This study aimed to systematically review the prevalence of dyslipidemia among Iranian children and adolescents. Materials and Methods: An electronic search was conducted on studies published from January 1990 to January 2014. The main international electronic data sources were PubMed and the NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS. For Persian databases, we used domestic databases with systematic search capability including IranMedex, Irandoc, and Scientific Information Database (SID). We included all available population-based studies and national surveys conducted in the pediatric age group (aged <21 years). Results: In this review, 1772 articles were identified (PubMed: 1464; Scopus: 11; ISI: 58; SID: 90; IranMedex: 149; Irandoc: 57). During three refine steps and after removing of duplicates, 182 articles related to the study domain were selected. After quality assessment, 46 studies were selected for text appraisal, of which 26 qualified articles were evaluated at the final step. The prevalence range of hypercholesterolemia, hypertriglyceridemia, elevated low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol (HDL-C) were 3-48%, 3-50%, 5-20% and 5-88%, respectively. Low HDL-C and hypertriglyceridemia were the most prevalent lipid disorders in this group of population. Conclusion: Dyslipidemia is a common health problem among Iranian children and adolescents. Few data were available in preschool children. This finding provides useful information for health policy makers to implement action-oriented interventions for prevention and early control of this important CVD risk factor.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=5;spage=503;epage=521;aulast=HovsepianDyslipidemiaIranlipid profilepediatricsprevalencesystematic review |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Silva Hovsepian Roya Kelishadi Shirin Djalalinia Farshad Farzadfar Shohreh Naderimagham Mostafa Qorbani |
spellingShingle |
Silva Hovsepian Roya Kelishadi Shirin Djalalinia Farshad Farzadfar Shohreh Naderimagham Mostafa Qorbani Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review Journal of Research in Medical Sciences Dyslipidemia Iran lipid profile pediatrics prevalence systematic review |
author_facet |
Silva Hovsepian Roya Kelishadi Shirin Djalalinia Farshad Farzadfar Shohreh Naderimagham Mostafa Qorbani |
author_sort |
Silva Hovsepian |
title |
Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review |
title_short |
Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review |
title_full |
Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review |
title_fullStr |
Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review |
title_full_unstemmed |
Prevalence of dyslipidemia in Iranian children and adolescents: A systematic review |
title_sort |
prevalence of dyslipidemia in iranian children and adolescents: a systematic review |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Research in Medical Sciences |
issn |
1735-1995 1735-7136 |
publishDate |
2015-01-01 |
description |
Background: Dyslipidemia is considered as an important modifiable risk factor for cardiovascular disease (CVD). The link between childhood dyslipidemia and occurrence of atherosclerosis and its sequels in adulthood are well-documented. This study aimed to systematically review the prevalence of dyslipidemia among Iranian children and adolescents. Materials and Methods: An electronic search was conducted on studies published from January 1990 to January 2014. The main international electronic data sources were PubMed and the NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), and SCOPUS. For Persian databases, we used domestic databases with systematic search capability including IranMedex, Irandoc, and Scientific Information Database (SID). We included all available population-based studies and national surveys conducted in the pediatric age group (aged <21 years). Results: In this review, 1772 articles were identified (PubMed: 1464; Scopus: 11; ISI: 58; SID: 90; IranMedex: 149; Irandoc: 57). During three refine steps and after removing of duplicates, 182 articles related to the study domain were selected. After quality assessment, 46 studies were selected for text appraisal, of which 26 qualified articles were evaluated at the final step. The prevalence range of hypercholesterolemia, hypertriglyceridemia, elevated low-density lipoprotein cholesterol, and low high-density lipoprotein cholesterol (HDL-C) were 3-48%, 3-50%, 5-20% and 5-88%, respectively. Low HDL-C and hypertriglyceridemia were the most prevalent lipid disorders in this group of population. Conclusion: Dyslipidemia is a common health problem among Iranian children and adolescents. Few data were available in preschool children. This finding provides useful information for health policy makers to implement action-oriented interventions for prevention and early control of this important CVD risk factor. |
topic |
Dyslipidemia Iran lipid profile pediatrics prevalence systematic review |
url |
http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2015;volume=20;issue=5;spage=503;epage=521;aulast=Hovsepian |
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