Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety
A series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by 1H-NMR, MS and elemental analysis...
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MDPI AG
2015-11-01
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| Series: | Applied Sciences |
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| Online Access: | http://www.mdpi.com/2076-3417/5/4/1211 |
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doaj-48691d92e91a4368850997ff3b0d08222020-11-25T00:49:05ZengMDPI AGApplied Sciences2076-34172015-11-01541211122010.3390/app5041211app5041211Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole MoietyLi-Jing Min0Yan-Xia Shi1Hong-Ke Wu2Zhao-Hui Sun3Xing-Hai Liu4Bao-Ju Li5Yong-Gang Zhang6College of Life Science, Huzhou University, Huzhou 313000, ChinaInstitute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100014, ChinaCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, ChinaCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, ChinaInstitute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100014, ChinaEcology Institute of Shandong Academy of Science, Jinan 250014, ChinaA series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by 1H-NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The results indicated that some of title compounds exhibited moderate antifungal activity.http://www.mdpi.com/2076-3417/5/4/1211thioether1,2,4-triazolemicrowave assistant synthesisantifungal activity |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Li-Jing Min Yan-Xia Shi Hong-Ke Wu Zhao-Hui Sun Xing-Hai Liu Bao-Ju Li Yong-Gang Zhang |
| spellingShingle |
Li-Jing Min Yan-Xia Shi Hong-Ke Wu Zhao-Hui Sun Xing-Hai Liu Bao-Ju Li Yong-Gang Zhang Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety Applied Sciences thioether 1,2,4-triazole microwave assistant synthesis antifungal activity |
| author_facet |
Li-Jing Min Yan-Xia Shi Hong-Ke Wu Zhao-Hui Sun Xing-Hai Liu Bao-Ju Li Yong-Gang Zhang |
| author_sort |
Li-Jing Min |
| title |
Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety |
| title_short |
Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety |
| title_full |
Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety |
| title_fullStr |
Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety |
| title_full_unstemmed |
Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety |
| title_sort |
microwave-assisted synthesis and antifungal activity of some novel thioethers containing 1,2,4-triazole moiety |
| publisher |
MDPI AG |
| series |
Applied Sciences |
| issn |
2076-3417 |
| publishDate |
2015-11-01 |
| description |
A series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by 1H-NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The results indicated that some of title compounds exhibited moderate antifungal activity. |
| topic |
thioether 1,2,4-triazole microwave assistant synthesis antifungal activity |
| url |
http://www.mdpi.com/2076-3417/5/4/1211 |
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