Cushing’s disease – Same condition, different scenarios
Cushing’s disease is a rare pathology characterized by excess production of adrenocorticotropic hormone (ACTH) secondary to a pituitary adenoma which stimulates adrenal cortisol secretion. The main consequences are the metabolic and cardiovascular complications, as well as osteoporosis and infe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Balkan Medical Union
2018-03-01
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Series: | Archives of the Balkan Medical Union |
Subjects: | |
Online Access: | http://umbalk.org/wp-content/uploads/2018/03/21.CUSHING%E2%80%99S-DISEASE-%E2%80%93-SAME-CONDITION-DIFFERENT.pdf |
Summary: | Cushing’s disease is a rare pathology characterized by
excess production of adrenocorticotropic hormone
(ACTH) secondary to a pituitary adenoma which
stimulates adrenal cortisol secretion. The main consequences
are the metabolic and cardiovascular complications,
as well as osteoporosis and infection predisposition,
which increase mortality in untreated patients.
The first case presentation is about a patient with
Cushing’s disease, surgically treated and cured, without
any need for substitution or signs of pituitary-adrenal
axis failure. The second case is a patient diagnosed
with Cushing’s disease, with multiple complications,
with clinical and hormonal relapse after selective adenomectomy
and resistant to medical therapy, who is
scheduled for reintervention. The third presentation
is about a patient known with osteoporosis, diagnosed
with Cushing’s disease based on the clinical appearance
with bilateral adrenal adenomas, with left suprarenalectomy
and pituitary gamma knife radiotherapy.
We aim to introduce a pictorial assay consisting of a
series of three cases, different from detection, management
and outcome |
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ISSN: | 1584-9244 2558-815X |