A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1

A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1

The concentration of selenium-binding protein1 (SBP1) is often lower in tumors than in the corresponding tissue and lower levels have been associated with poor clinical outcomes. SBP1 binds tightly selenium although what role selenium plays in its biological functions remains unknown. Previous studi...

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Bibliographic Details
Main Authors: Qi Ying, Emmanuel Ansong, Alan M. Diamond, Wancai Yang
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
selenium-binding protein1
glutathione peroxidase 1
selenite cytotoxicity
mitochondrial damage
Online Access:http://www.mdpi.com/1422-0067/16/11/26043

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