Live imaging-based model selection reveals periodic regulation of the stochastic G1/S phase transition in vertebrate axial development.

In multicellular organism development, a stochastic cellular response is observed, even when a population of cells is exposed to the same environmental conditions. Retrieving the spatiotemporal regulatory mode hidden in the heterogeneous cellular behavior is a challenging task. The G1/S transition o...

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Bibliographic Details
Main Authors: Mayu Sugiyama, Takashi Saitou, Hiroshi Kurokawa, Asako Sakaue-Sawano, Takeshi Imamura, Atsushi Miyawaki, Tadahiro Iimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4256085?pdf=render