Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection
Polyquinone derivatives are widely recognized in the literature for their remarkable properties, their biocompatibility, simple synthesis, and easy bio-functionalization. We have shown that polyquinones present very stable electroactivity in neutral aqueous medium within the cathodic potential domai...
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doaj-48af37ed06f64271911ff8499ed7c4cb2020-11-24T22:18:04ZengMDPI AGBiosensors2079-63742013-01-0131587610.3390/bios3010058Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides DetectionMinh-Chau PhamHuynh-Thien DucGuillaume AnquetinSteeve ReisbergBenoit PiroPolyquinone derivatives are widely recognized in the literature for their remarkable properties, their biocompatibility, simple synthesis, and easy bio-functionalization. We have shown that polyquinones present very stable electroactivity in neutral aqueous medium within the cathodic potential domain avoiding side oxidation of interfering species. Besides, they can act as immobilized redox transducers for probing biomolecular interactions in sensors. Our group has been working on devices based on such modified electrodes with a view to applications for proteins, antibodies and organic pollutants using a reagentless label-free electrochemical immunosensor format. Herein, these developments are briefly reviewed and put into perspective.http://www.mdpi.com/2079-6374/3/1/58conducting polymersquare wave voltammetryimpedance spectroscopyimmunosensorproteinspeptidespollutantselectrochemical biosensorlabel-free detection |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Minh-Chau Pham Huynh-Thien Duc Guillaume Anquetin Steeve Reisberg Benoit Piro |
spellingShingle |
Minh-Chau Pham Huynh-Thien Duc Guillaume Anquetin Steeve Reisberg Benoit Piro Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection Biosensors conducting polymer square wave voltammetry impedance spectroscopy immunosensor proteins peptides pollutants electrochemical biosensor label-free detection |
author_facet |
Minh-Chau Pham Huynh-Thien Duc Guillaume Anquetin Steeve Reisberg Benoit Piro |
author_sort |
Minh-Chau Pham |
title |
Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection |
title_short |
Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection |
title_full |
Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection |
title_fullStr |
Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection |
title_full_unstemmed |
Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection |
title_sort |
quinone-based polymers for label-free and reagentless electrochemical immunosensors: application to proteins, antibodies and pesticides detection |
publisher |
MDPI AG |
series |
Biosensors |
issn |
2079-6374 |
publishDate |
2013-01-01 |
description |
Polyquinone derivatives are widely recognized in the literature for their remarkable properties, their biocompatibility, simple synthesis, and easy bio-functionalization. We have shown that polyquinones present very stable electroactivity in neutral aqueous medium within the cathodic potential domain avoiding side oxidation of interfering species. Besides, they can act as immobilized redox transducers for probing biomolecular interactions in sensors. Our group has been working on devices based on such modified electrodes with a view to applications for proteins, antibodies and organic pollutants using a reagentless label-free electrochemical immunosensor format. Herein, these developments are briefly reviewed and put into perspective. |
topic |
conducting polymer square wave voltammetry impedance spectroscopy immunosensor proteins peptides pollutants electrochemical biosensor label-free detection |
url |
http://www.mdpi.com/2079-6374/3/1/58 |
work_keys_str_mv |
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