Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer

Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer

<p>Abstract</p> <p>Background</p> <p>Chemotherapy for pancreatic carcinoma often has severe side effects that limit its efficacy. The glucocorticoid (GC) dexamethasone (DEX) is frequently used as co-treatment to prevent side effects of chemotherapy such as nausea, for p...

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Bibliographic Details
Main Authors: Debatin Klaus-Michael, Edler Lutz, Rittgen Werner, Mattern Jürgen, Cato Andrew CB, Büchler Peter, Kolb Armin, Zhang Chengwen, Büchler Markus W, Friess Helmut, Herr Ingrid
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/61

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