Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study.

Addition of a polygenic risk score, mammographic density, and endogenous hormones to existing breast cancer risk prediction models: A nested case-control study.

<h4>Background</h4>No prior study to our knowledge has examined the joint contribution of a polygenic risk score (PRS), mammographic density (MD), and postmenopausal endogenous hormone levels-all well-confirmed risk factors for invasive breast cancer-to existing breast cancer risk predic...

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Bibliographic Details
Main Authors: Xuehong Zhang, Megan Rice, Shelley S Tworoger, Bernard A Rosner, A Heather Eliassen, Rulla M Tamimi, Amit D Joshi, Sara Lindstrom, Jing Qian, Graham A Colditz, Walter C Willett, Peter Kraft, Susan E Hankinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002644

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