Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion
Pulmonary tuberculosis is a common infection worldwide. In the eastern part of Iran, fluctuations in tuberculosis prevalence are seen due to the migration of people from Afghanistan. The aim of this study was to evaluate the time of bacteriologic sputum conversion after treatment and affecting facto...
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Shiraz University of Medical Sciences
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doaj-490566c31cb24ccc8433341558c476502020-11-25T02:05:46ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882016-01-014114447Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed ConversionZohreh Azarkar0Gholamreza Sharifzadeh1Azade Ebrahimzadeh2Saeeid Olumi3Hepatitis Research Center, Department of Infectious Disease, School of Medicine, Birjand University of Medical Sciences, Birjand, IranDepartment of Public Health, School of Health, Birjand University of Medical Sciences, Birjand, IranHepatitis Research Center, Department of Infectious Disease, School of Medicine, Birjand University of Medical Sciences, Birjand, IranSchool of Medicine, Birjand University of Medical Sciences, Birjand, IranPulmonary tuberculosis is a common infection worldwide. In the eastern part of Iran, fluctuations in tuberculosis prevalence are seen due to the migration of people from Afghanistan. The aim of this study was to evaluate the time of bacteriologic sputum conversion after treatment and affecting factors in those whose smear does not become negative. This study was carried out on 85 smear-positive pulmonary tuberculosis patients with the mean age of 65.6±16.7 years. There were 38 male patients (44.7%), 47 urban residents (55.3%), and only 6 patients (7.1%) from Afghanistan. The mean time of sputum conversion after starting treatment was 1.99±1.06 months. The mean time of sputum conversion was significantly higher in males (P=0.046), increased bacilli density in the primary sputum sample (P<0.0001, R=0.507), and pre-existing medical illness (P=0.001). In this study, it was revealed that pre-existing illness, bacilli density in initial smear, and severe involvement of the lung on radiography, could be associated with delay in sputum smear conversion.http://ijms.sums.ac.ir/index.php/IJMS/article/view/634RadiographySputumPulmonary tuberculosisBacteriologic conversion |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zohreh Azarkar Gholamreza Sharifzadeh Azade Ebrahimzadeh Saeeid Olumi |
spellingShingle |
Zohreh Azarkar Gholamreza Sharifzadeh Azade Ebrahimzadeh Saeeid Olumi Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion Iranian Journal of Medical Sciences Radiography Sputum Pulmonary tuberculosis Bacteriologic conversion |
author_facet |
Zohreh Azarkar Gholamreza Sharifzadeh Azade Ebrahimzadeh Saeeid Olumi |
author_sort |
Zohreh Azarkar |
title |
Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion |
title_short |
Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion |
title_full |
Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion |
title_fullStr |
Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion |
title_full_unstemmed |
Time to Sputum Smear Conversion in Smear-Positive Pulmonary Tuberculosis Patients and Factors for Delayed Conversion |
title_sort |
time to sputum smear conversion in smear-positive pulmonary tuberculosis patients and factors for delayed conversion |
publisher |
Shiraz University of Medical Sciences |
series |
Iranian Journal of Medical Sciences |
issn |
0253-0716 1735-3688 |
publishDate |
2016-01-01 |
description |
Pulmonary tuberculosis is a common infection worldwide. In the eastern part of Iran, fluctuations in tuberculosis prevalence are seen due to the migration of people from Afghanistan. The aim of this study was to evaluate the time of bacteriologic sputum conversion after treatment and affecting factors in those whose smear does not become negative. This study was carried out on 85 smear-positive pulmonary tuberculosis patients with the mean age of 65.6±16.7 years. There were 38 male patients (44.7%), 47 urban residents (55.3%), and only 6 patients (7.1%) from Afghanistan. The mean time of sputum conversion after starting treatment was 1.99±1.06 months. The mean time of sputum conversion was significantly higher in males (P=0.046), increased bacilli density in the primary sputum sample (P<0.0001, R=0.507), and pre-existing medical illness (P=0.001). In this study, it was revealed that pre-existing illness, bacilli density in initial smear, and severe involvement of the lung on radiography, could be associated with delay in sputum smear conversion. |
topic |
Radiography Sputum Pulmonary tuberculosis Bacteriologic conversion |
url |
http://ijms.sums.ac.ir/index.php/IJMS/article/view/634 |
work_keys_str_mv |
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