Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis
Abstract Background Some previous studies have reported inconsistent results on the association between alcohol intake and diabetic retinopathy (DR) risk. This study aimed to evaluate the potential effects of alcohol intake on subsequent DR risk using a meta-analytic approach. Methods Three electron...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
|
Series: | BMC Endocrine Disorders |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12902-020-00588-3 |
id |
doaj-4936c01ce7ed4d4cbaded1a1649b28fd |
---|---|
record_format |
Article |
spelling |
doaj-4936c01ce7ed4d4cbaded1a1649b28fd2020-11-25T03:51:57ZengBMCBMC Endocrine Disorders1472-68232020-07-0120111010.1186/s12902-020-00588-3Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysisChen Chen0Zhaojun Sun1Weigang Xu2Jun Tan3Dan Li4Yiting Wu5Ting Zheng6Derong Peng7Shanghai Jing ‘an District Jiangning Road Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterShanghai Jing ‘an District Pengpuxincun Community Health Service CenterAbstract Background Some previous studies have reported inconsistent results on the association between alcohol intake and diabetic retinopathy (DR) risk. This study aimed to evaluate the potential effects of alcohol intake on subsequent DR risk using a meta-analytic approach. Methods Three electronic databases (PubMed, EmBase, and the Cochrane library) were systematically searched for observational studies from their inception till November 2019. The pooled odds ratio (OR) with 95% confidence interval (CI) were applied for the summary effect estimate using a random-effects model. Results A total of 15 studies (5 cohort studies, 4 case-control studies, and 6 cross-sectional studies) with 37,290 participants and 12,711 DR cases were selected for the final meta-analysis. The pooled OR indicated no significant association between alcohol intake and DR risk (OR: 0.91; 95%CI: 0.78–1.06; P = 0.225), irrespective of the studies being pooled cohort (OR: 0.95; 95%CI: 0.66–1.36; P = 0.761), case-control (OR: 0.97; 95%CI: 0.77–1.23; P = 0.818), or cross-sectional (OR: 0.86; 95%CI: 0.69–1.08; P = 0.190) ones. However, this association might have been affected by the type of diabetes mellitus and the adjusted status. Conclusion The results of this study showed that the potential impact of alcohol intake on DR risk may differ according to the type of diabetes mellitus and adjusted status. Further large-scale, prospective cohort studies should be conducted to verify the findings of this study and to evaluate DR risk in relation to the dose and type of alcohol intake.http://link.springer.com/article/10.1186/s12902-020-00588-3AlcoholDiabetic retinopathyMeta-analysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chen Chen Zhaojun Sun Weigang Xu Jun Tan Dan Li Yiting Wu Ting Zheng Derong Peng |
spellingShingle |
Chen Chen Zhaojun Sun Weigang Xu Jun Tan Dan Li Yiting Wu Ting Zheng Derong Peng Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis BMC Endocrine Disorders Alcohol Diabetic retinopathy Meta-analysis |
author_facet |
Chen Chen Zhaojun Sun Weigang Xu Jun Tan Dan Li Yiting Wu Ting Zheng Derong Peng |
author_sort |
Chen Chen |
title |
Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis |
title_short |
Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis |
title_full |
Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis |
title_fullStr |
Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis |
title_full_unstemmed |
Associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis |
title_sort |
associations between alcohol intake and diabetic retinopathy risk: a systematic review and meta-analysis |
publisher |
BMC |
series |
BMC Endocrine Disorders |
issn |
1472-6823 |
publishDate |
2020-07-01 |
description |
Abstract Background Some previous studies have reported inconsistent results on the association between alcohol intake and diabetic retinopathy (DR) risk. This study aimed to evaluate the potential effects of alcohol intake on subsequent DR risk using a meta-analytic approach. Methods Three electronic databases (PubMed, EmBase, and the Cochrane library) were systematically searched for observational studies from their inception till November 2019. The pooled odds ratio (OR) with 95% confidence interval (CI) were applied for the summary effect estimate using a random-effects model. Results A total of 15 studies (5 cohort studies, 4 case-control studies, and 6 cross-sectional studies) with 37,290 participants and 12,711 DR cases were selected for the final meta-analysis. The pooled OR indicated no significant association between alcohol intake and DR risk (OR: 0.91; 95%CI: 0.78–1.06; P = 0.225), irrespective of the studies being pooled cohort (OR: 0.95; 95%CI: 0.66–1.36; P = 0.761), case-control (OR: 0.97; 95%CI: 0.77–1.23; P = 0.818), or cross-sectional (OR: 0.86; 95%CI: 0.69–1.08; P = 0.190) ones. However, this association might have been affected by the type of diabetes mellitus and the adjusted status. Conclusion The results of this study showed that the potential impact of alcohol intake on DR risk may differ according to the type of diabetes mellitus and adjusted status. Further large-scale, prospective cohort studies should be conducted to verify the findings of this study and to evaluate DR risk in relation to the dose and type of alcohol intake. |
topic |
Alcohol Diabetic retinopathy Meta-analysis |
url |
http://link.springer.com/article/10.1186/s12902-020-00588-3 |
work_keys_str_mv |
AT chenchen associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT zhaojunsun associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT weigangxu associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT juntan associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT danli associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT yitingwu associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT tingzheng associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis AT derongpeng associationsbetweenalcoholintakeanddiabeticretinopathyriskasystematicreviewandmetaanalysis |
_version_ |
1724485315728506880 |