Constituintes químicos e avaliação das atividades antioxidante e anti-inflamatória das raízes de Sabicea brasiliensis wernh (Rubiaceae)

• Main Authors: Jucilene Cavalini Batista, Silvana Maria de Oliveira Santin, Ivânia T. Albrecht Schuquel, Laura Lícia Milani de Arruda, Ciomar Aparecida Bersani-Amado, Cecília Maria Alves de Oliveira, Lucilia Kato, Heleno Dias Ferreira, Cleuza Conceição da Silva
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Química 2014-01-01
• Series: Química Nova
• Subjects: Sabicea brasiliensis; caffeoylquinic acid; anti-inflammatory activity
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400010&lng=en&tlng=en
• ISSN: 1678-7064

The phytochemical investigation of Sabicea brasiliensis roots led to the isolation of 5-O-caffeoylquinic acid, 3,5- and 4,5-O-dicaffeoylquinics acids, scopoletin, ursolic acid, a mixture of β-sitosterol, stigmasterol and campesterol, daucosterol and saccharose. The structures of the isolated compounds were assigned on the basis of one- and two-dimensional NMR spectroscopic methods and by comparison with literature data. The anti-inflammatory and antioxidant activities of the crude methanolic extract and its fractions were analyzed.