A rare case of toxic epidermolysis necrolysis in early infancy: Successfully treated with intravenous immunoglobulin

Toxic epidermal necrolysis (TEN) is a potentially life-threatening dermatological disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and/or death. TEN is a disease of both children and ad...

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Bibliographic Details
Main Authors: Bharti Bhandari, Ragini Singh, Mritunjay Kumar, Aditya Saun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Paediatric Dermatology
Subjects:
Online Access:http://www.ijpd.in/article.asp?issn=2319-7250;year=2019;volume=20;issue=3;spage=258;epage=260;aulast=Bhandari
Description
Summary:Toxic epidermal necrolysis (TEN) is a potentially life-threatening dermatological disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis and/or death. TEN is a disease of both children and adults, but TEN in early infancy is a rare event; in literature, only few cases in infants aged <6 months have been reported so far. We reported a case of a 6-week-old infant who developed TEN after some local off-label medication for abdominal colic. After intravenous immunoglobulin treatment, the infant showed dramatic improvement without any complications.
ISSN:2319-7250